ChemicalBook > CAS DataBase List > 1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea

1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea

Product Name
1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea
CAS No.
128831-46-9
Chemical Name
1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea
Synonyms
TMP153,TMP 153;N-(4-(2-chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea;1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea;Urea, N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)-
CBNumber
CB61260977
Molecular Formula
C24H18ClF2N3O
Formula Weight
437.87
MOL File
128831-46-9.mol
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1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Property

Melting point:
approximate 217℃
storage temp. 
Store at -20°C
solubility 
DMF: 10 mg/ml,DMSO: 30 mg/ml
form 
White solid.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010516
Product name
TMP-153
Purity
≥95%
Packaging
5mg
Price
$28
Updated
2023/01/06
Cayman Chemical
Product number
10010516
Product name
TMP-153
Purity
≥95%
Packaging
10mg
Price
$50
Updated
2023/01/06
Cayman Chemical
Product number
10010516
Product name
TMP-153
Purity
≥95%
Packaging
25mg
Price
$76
Updated
2023/01/06
AK Scientific
Product number
8948CA
Product name
N-(4-(2-Chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea
Packaging
5mg
Price
$133
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0000235
Product name
TMP-153
Purity
95.00%
Packaging
25MG
Price
$184.8
Updated
2021/12/16
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1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Chemical Properties,Usage,Production

Uses

TMP-153 is an orally active inhibitor of ACAT with an IC50 value of approximately 5-10 nM against hepatic and intestinal ACAT in varicose animals. TMP-153 exhibits cholesterol-lowering effects and can be utilized in the research of atherosclerosis[1].

References

[1] Sugiyama Y, et al. TMP-153, a novel ACAT inhibitor, inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters. Atherosclerosis. 1995;113(1):71-78. DOI:10.1016/0021-9150(94)05429-m

1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Suppliers

China 14 Germany 1 United States 5 Global 20
Shanghai EFE Biological Technology Co., Ltd.
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sales@glpbio.cn
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128831-46-9, 1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)ureaRelated Search:

pyripyropene A 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) S-nitrosocaptopril ABZ-PHE-ARG-LYS(DNP)-PRO-OH

  • 1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea
  • N-(4-(2-chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea
  • Urea, N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)-
  • TMP153,TMP 153
  • 128831-46-9
  • C24H18ClF2N3O
  • C24H18N3OF2Cl