ChemicalBook > CAS DataBase List > Akebia saponin D

Akebia saponin D

Product Name
Akebia saponin D
CAS No.
39524-08-8
Chemical Name
Akebia saponin D
Synonyms
Asperosap;AkebosideD;Asperosaponin Ⅵ;Asperosaponin VI;Akebia saponin D;Dipsacaceae saponin;Asperosaponin VI-RM;Akebia saponin D USP/EP/BP;Asperosaponin VI (Akeboside D);Asperosaponin VI, 10 mM in DMSO
CBNumber
CB61267734
Molecular Formula
C47H76O18
Formula Weight
929.1
MOL File
39524-08-8.mol
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Akebia saponin D Property

Melting point:
234-235 °C
Boiling point:
990.2±65.0 °C(Predicted)
Density 
1.43
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
form 
Solid
pka
12.50±0.70(Predicted)
color 
White to Pale Beige
optical activity
[α]/D +13 to +18°, c =0.5 in methanol
biological source
(Dipsacus asper)
Water Solubility 
H2O: 3mg/mL, clear (warmed)
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Safety

Safety Statements 
24/25
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL83275
Product name
Asperosaponin VI
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$550
Updated
2024/03/01
TRC
Product number
A788600
Product name
AsperosaponinVI
Packaging
10mg
Price
$150
Updated
2021/12/16
Usbiological
Product number
299958
Product name
Asperosaponin VI
Packaging
20mg
Price
$390
Updated
2021/12/16
ChemScene
Product number
CS-0008286
Product name
AsperosaponinVI
Purity
98.73%
Packaging
20mg
Price
$150
Updated
2021/12/16
Biorbyt Ltd
Product number
orb104638
Product name
Akebia saponin D
Purity
>98%,Standard References Grade
Packaging
20mg
Price
$569.5
Updated
2021/12/16
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Akebia saponin D Chemical Properties,Usage,Production

Uses

Asperosaponin VI is a steroidal extract with anti-inflammatory and antinociceptive activity. long term use has been seen to attenuate cardiac dysfunction.

Definition

ChEBI: Akebia saponin D is a triterpenoid saponin that is hederagenin attached to a alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage and a 6-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl residue at position 28 via an ester linkage. It is the active ingredient found in the traditional Chinese herb Radix Dipsaci. It has a role as an apoptosis inducer, an antineoplastic agent, a plant metabolite, an anti-inflammatory agent, a bone density conservation agent, a neuroprotective agent and an antilipemic drug. It is a triterpenoid saponin, a trisaccharide derivative, a pentacyclic triterpenoid and a carboxylic ester. It is functionally related to a hederagenin.

Biological Activity

Akebia saponin D (ASD) is a bioactive triterpenoid saponin isolated from the rhizome of Dipsacus asper Wall th at is used as an anti-osteoporosis drug. Akebia saponin D exhibits therapeutic effects in number of disease models including cancer, Alzheimerμs disease, cardiovascular disease, and bone fractures. Akebia saponin D protects against nonalcoholic fatty liver disease (NAFLD) liver damage in mice model of NAFLD. ASD decreases hepatic steatosis and heptocyte apoptosis through autophagy modulation. Akebia saponin D prevents oleic acid induced lipid droplets accumulation and increases autophagic flux BRL cells.

Akebia saponin D Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Akebia saponin D manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Akebia saponin D 39524-08-8
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-09-29
Shanghai Standard Technology Co., Ltd.
Product
Akebia saponin D 39524-08-8
Price
US $0.00/mg
Min. Order
5mg
Purity
Analytical Standard
Supply Ability
10 g
Release date
2019-09-29
Career Henan Chemical Co
Product
Akebia saponin D 39524-08-8
Price
US $2.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10000kg
Release date
2018-08-10

39524-08-8, Akebia saponin DRelated Search:

Pennogenin 3-O-alpha-L-rhamnopyranosyl-(1-2)-beta-D-xylopyranosyl-(1-4)-beta-D-glucopyranoside 4'-O-Acetyl-akebia saponin D Dipsanoside A 3-[[2-O-(α-L-Rhamnopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxyolean-12-en-28-oic acid Dipsanoside B oleanolic acid-3-O-β-D-glucopyranosyl (1→2)-α-L-arabinopyranoside Sylvestroside I dipsacoside B (3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside TRIBULOSIDE Saponin

  • Akebia saponin D
  • Asperosaponin VI
  • Hederagenin 3-O-alpha-L-arabinopyranosyl-28-beta-D-glucopyranosyl(1→6)-beta-D-glucopyranoside
  • Akebia saponin D(Asperosaponin VI)
  • Dipsacaceae saponin
  • 3'-Amino-2'-Hydroxy-1,1' biphenyl-3-cAsperosaponin VI
  • Asperosaponin VI, 98%, from Dipsacales
  • Asperosaponin Ⅵ
  • Asperosaponin VI (Akeboside D)
  • AkebosideD
  • Olean-12-en-28-oic acid, 3-(α-L-arabinopyranosyloxy)-23-hydroxy-, 6-O-β-D-glucopyranosyl-β-D-glucopyranosyl ester, (3β,4α)-
  • Akebia saponin D USP/EP/BP
  • TIANFUCHEM--39524-08-8--High purity Akebia saponin D factory price
  • Asperosap
  • 1-O-[(3b)-3-(a-L-Arabinopyranosyloxy)-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-D-glucopyranosyl-b-D-glucopyranose
  • (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl (4aS,6aS,6bR,8aR,9R,10S,12aR,12bR,14bS)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-(((2S,3R,4S,5S)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate
  • Asperosaponin VI-RM
  • 3’-Amino-2’-Hydroxy-1,1’ biphenyl-3-cAsperosaponin VI
  • Asperosaponin VI, 10 mM in DMSO
  • 39524-08-8
  • C47H76O18
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract