ChemicalBook > CAS DataBase List > 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)

5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)

Product Name
5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)
CAS No.
350847-80-2
Chemical Name
5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)
Synonyms
6,7-dihydro-5H-cyclopenta[c]pyridin-5-one;6,7-Dihydro-5H-[2]pyrindin-5-one;5H,6H,7H-cyclopenta[c]pyridin-5-one;6,7-dihydrocyclopenta[c]pyridin-5-one;6,7-dihydro-1H-cyclopenta[c]pyridin-5-one;6,7-Dihydro-5H-cyclopental[c]pyridin-5-one;6,7-Dihydro-5H-cyclopental[c]pyridine-5-one;5H-Cyclopenta[c]pyridin-5-one, 6,7-dihydro-;5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)
CBNumber
CB61271740
Molecular Formula
C8H7NO
Formula Weight
133.15
MOL File
350847-80-2.mol
More
Less

5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) Property

Boiling point:
267.4±9.0 °C(Predicted)
Density 
1.230±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
pka
3.56±0.20(Predicted)
Appearance
Brown to black Solid
More
Less

Safety

HazardClass 
IRRITANT
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
D456045
Product name
6,7-dihydro-5H-cyclopenta[c]pyridin-5-one
Packaging
100mg
Price
$200
Updated
2021/12/16
AK Scientific
Product number
4302AB
Product name
6,7-Dihydro-5H-cyclopenta[c]pyridin-5-one
Packaging
250mg
Price
$317
Updated
2021/12/16
J&W Pharmlab
Product number
69R0625
Product name
6,7-Dihydro-[2]pyrindin-5-one
Purity
98%
Packaging
50mg
Price
$131
Updated
2021/12/16
J&W Pharmlab
Product number
69R0625
Product name
6,7-Dihydro-[2]pyrindin-5-one
Purity
98%
Packaging
100mg
Price
$163
Updated
2021/12/16
J&W Pharmlab
Product number
69R0625
Product name
6,7-Dihydro-[2]pyrindin-5-one
Purity
98%
Packaging
250mg
Price
$225
Updated
2021/12/16
More
Less

5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) Chemical Properties,Usage,Production

Synthesis

19608-41-4

350847-80-2

General procedure for the synthesis of 6,7-dihydro-5H-cyclopentadieno[c]pyridin-5-one from methyl 3-(3-ethoxy-3-oxopropyl)isonicotinate: to a tetrahydrofuran (THF, 5.0 mL) solution of methyl 3-(3-ethoxy-3-oxopropyl)isonicotinate (300 mg, 1.26 mmol) was added potassium 2-methylpropan-2-ol ( 0.28 g, 2.52 mmol). The reaction mixture was stirred at room temperature for 1 hour. Subsequently, the solvent was evaporated to dryness. Concentrated hydrochloric acid (5 mL) was added to the residue and the reaction mixture was stirred at 100 °C for 2 hours. After continuing to stir at 100 °C for 16 h, saturated aqueous sodium bicarbonate (40 mL) and ethyl acetate (EtOAc, 50 mL) were added to the reaction vessel, and the resulting two-phase mixture was transferred to a partition funnel. The organic and aqueous layers were separated and the aqueous phase was extracted with ethyl acetate (2 x 50 mL). The organic phases were combined, washed with saturated saline, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting oil was purified by fast column chromatography using isocratic elution conditions of ethyl acetate (35%) and hexane (65%) to afford 6,7-dihydro-5H-cyclopenta[c]pyridin-5-one (0.03 g, 0.23 mmol) as a gray oil.

References

[1] Patent: WO2018/26371, 2018, A1. Location in patent: Paragraph 0132; 0134; 0283

5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI) Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
LABTER PHARMATECH(BEIJING) CO.,LTD
Tel
010-56330744 18310155299
Fax
010-56330744
Email
sales@labter.com.cn
Country
China
ProdList
20000
Advantage
55
Zhengzhou AiXi Technology Co., Ltd.
Tel
0371-56787280 13137706083
Fax
-
Email
m18539565376@163.com
Country
China
ProdList
970
Advantage
55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Shanghai WangFa Chemical Technology Co., Ltd.
Tel
13918479294
Fax
-
Email
xiebenfa@163.com
Country
China
ProdList
4092
Advantage
58
Bejing Famous Pharmaceutical Technology Co., Ltd.
Tel
13331045123
Fax
86-10-80339217
Email
2559355526@qq.com
Country
China
ProdList
14193
Advantage
58
Shanghai Benso Pharmaceutical Technology Co., Ltd.
Tel
15088289376
Email
248775804@qq.com
Country
China
ProdList
4995
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58

350847-80-2, 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)Related Search:


  • 5H,6H,7H-cyclopenta[c]pyridin-5-one
  • 5H-Cyclopenta[c]pyridin-5-one, 6,7-dihydro-
  • 6,7-Dihydro-5H-[2]pyrindin-5-one
  • 6,7-dihydro-5H-cyclopenta[c]pyridin-5-one
  • 6,7-Dihydro-5H-cyclopental[c]pyridine-5-one
  • 6,7-dihydrocyclopenta[c]pyridin-5-one
  • 5H-Cyclopenta[c]pyridin-5-one,6,7-dihydro-(9CI)
  • 6,7-Dihydro-5H-cyclopental[c]pyridin-5-one
  • 6,7-dihydro-1H-cyclopenta[c]pyridin-5-one
  • 350847-80-2
  • PYRIDINE