TRIETHYL 2-PHOSPHONOBUTYRATE

Product Name: TRIETHYL 2-PHOSPHONOBUTYRATE
CAS No.: 17145-91-4
Chemical Name: TRIETHYL 2-PHOSPHONOBUTYRATE
Synonyms: Ethyl 2-(diethoxyphosphoryl)butanoate;Butanoic acid, 2-(diethoxyphosphinyl)-, ethyl ester;NSC 22423;TRIETHYL 2-PHOSPHONOBUTYRATE;TRIETHYL-2-PHOSPHONOBUTANOATE;Triethyl 2-phosphonobutyrate,98%;Triethyl alpha-phosphonobutyrate;Triethyl 2-phosphonobutyrate 98%;Triethyle2-phosphonobutyrate, 98%;Ethyl 2-(diethylphosphono)butyrate
CBNumber: CB6127879
Molecular Formula: C10H21O5P
Formula Weight: 252.24
MOL File: 17145-91-4.mol

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TRIETHYL 2-PHOSPHONOBUTYRATE Property

Boiling point:: 152-154 °C14 mm Hg(lit.)
Density: 1.064 g/mL at 25 °C(lit.)
refractive index: n20/D 1.432(lit.)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
form: Liquid
Specific Gravity: 1.064
color: Clear colorless
Water Solubility: Not miscible or difficult to mix with water.
BRN: 1789280
InChI: InChI=1S/C10H21O5P/c1-5-9(10(11)13-6-2)16(12,14-7-3)15-8-4/h9H,5-8H2,1-4H3
InChIKey: GYUCVQSNZFRDRL-UHFFFAOYSA-N
SMILES: C(OCC)(=O)C(P(OCC)(OCC)=O)CC

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29310099
Storage Class: 10 - Combustible liquids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 417467
Product name: Triethyl 2-phosphonobutyrate
Purity: 98%
Packaging: 5ml
Price: $57.1
Updated: 2023/06/20

TRC

Product number: T895923
Product name: Triethyl 2-phosphonobutyrate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: T895923
Product name: Triethyl 2-phosphonobutyrate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: T895923
Product name: Triethyl 2-phosphonobutyrate
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Oakwood

Product number: 003791
Product name: Triethyl 2-phosphonobutyrate
Packaging: 1g
Price: $11
Updated: 2021/12/16

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TRIETHYL 2-PHOSPHONOBUTYRATE Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Reactant used for preparation of furospinosulin-1 and analogs as hypoxia-selective antitumor agents, Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer?s drugs, phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents, PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists, notch-sparing γ-secretase inhibitors derived from PPAR agonist library and plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis.

Uses

Reactant for preparation of:

Furospinosulin-1 and analogs as hypoxia-selective antitumor agents
Aminoquinolines as beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors and potential anti-Alzheimer′s drugs
Phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists as nonalcoholic steatohepatitis (NASH)-preventive agents
PPAR agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related LXR antagonists
Notch-sparing γ-secretase inhibitors derived from PPAR agonist library
Plakotenin via Diels-Alder reaction, as a potential anticancer agent, naturally found in Okinawan sponge of the genus Plakortis
Quinone/naphthoquinone-substituted propenoic acids as inhibitors of cell growth and redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor 1 (Ape1/Ref-1)
α-alkenyl cyclic ethers by asymmetric dehydrative cyclization of ω-hydroxy allyl alcohols catalyzed by Ru complexes of axially chiral naphthylpyridinecarboxylates
Branched phosphonoethoxyethyl purines as new acyclic nucleoside phosphonates which inhibit Plasmodium falciparum (malarial parasite) hypoxanthine-guanine-xanthine phosphoribosyltransferase (HGXPRT)
Phenylpropanoic acid-type peroxisome proliferator-activated receptor pan agonists as candidate drugs for treatment of altered metabolic homeostasis

reaction suitability

reaction type: C-C Bond Formation

TRIETHYL 2-PHOSPHONOBUTYRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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TRIETHYL 2-PHOSPHONOBUTYRATE Suppliers

Belgium 1 China 108 France 2 Germany 2 India 1 Japan 1 Switzerland 1 United Kingdom 4 United States 8 Global 128

Energy Chemical

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View Lastest Price from TRIETHYL 2-PHOSPHONOBUTYRATE manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Triethyl 2-phosphonobutyrate 17145-91-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-03-20

Shanghai Bojing Chemical Co.,Ltd.

Product: TRIETHYL 2-PHOSPHONOBUTYRATE 17145-91-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20MT
Release date: 2024-03-13

Henan Fengda Chemical Co., Ltd

Product: TRIETHYL 2-PHOSPHONOBUTYRATE 17145-91-4
Price: US $8.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-23

17145-91-4, TRIETHYL 2-PHOSPHONOBUTYRATERelated Search:

Triethylamine trihydrofluoride triisopropylsilyl Methacrylate acetic acid, triethoxy-, ethyl ester TRIISOPROPYLSILYL TRIFLUOROMETHANESULFONATE Triethyloxonium tetrafluoroborate TRIETHYL 2-PHOSPHONOPROPIONATE 2-PHOSPHONOBUTYRIC ACID TRIETHYL 4-PHOSPHONOBUTYRATE TRIETHYL ALPHA-PROPARGYLPHOSPHONOACETATE 2-(DIETHOXYPHOSPHINYL)-3-METHYLBUTANOIC ACID ETHYL ESTER TRIETHYL 2-PHOSPHONOPENTANOATE 1-Ethyl 4-(tert-Butyl) 2-(diethyl phosphono)succinate TRIETHYL 2-PHOSPHONOBUTYRATE Triethyl phosphoroacetate Triethyl orthobutyrate Triethyl methanetricarboxylate Triethyl orthobenzoate Triethyl 1,1,2-ethanetricarboxylate

2-PHOSPHONOBUTYRIC ACID TRIETHYL ESTER

Diethyl 1-(ethoxycarbonyl)propanephosphonate~2-Phosphonobutyric acid triethyl ester

diethyl 1-(ethoxycarbonyl)propanephosphonate

Diethyl[1-(ethoxycarbonyl)propyl]phosphonate, 98 %

Ethyl 2-(diethoxyphosphoryl)butanoate

alpha-Diethylphosphonobutanoic acid ethyl ester

Ethyl 2-(diethoxyphosphinyl)butanoate

Ethyl 2-(diethylphosphono)butyrate

NSC 22423

Triethyl alpha-phosphonobutyrate

Triethyl 2-phosphonobutyrate,98%

α-Diethylphosphonobutanoic acid ethyl ester

Triethyl 2-phosphonobutyrate 98%

Triethyle2-phosphonobutyrate, 98%

TRIETHYL-2-PHOSPHONOBUTANOATE

TRIETHYL 2-PHOSPHONOBUTYRATE

DIETHYL[1-(ETHOXYCARBONYL)PROPYL]PHOSPHONATE

Butanoic acid, 2-(diethoxyphosphinyl)-, ethyl ester

2-(DIETHOXY-PHOSPHORYL)-BUTYRIC ACID ETHYL ESTER

17145-91-4

C2H5O2POCHC2H5CO2C2H5

C-C Bond Formation

Synthetic Reagents

Olefination

Horner-Wadsworth-Emmons Reagents

C-C Bond Formation

Horner-Wadsworth-Emmons Reagents

Olefination