1-(3-BROMOPHENYL)-1H-PYRAZOLE
- Product Name
- 1-(3-BROMOPHENYL)-1H-PYRAZOLE
- CAS No.
- 294877-33-1
- Chemical Name
- 1-(3-BROMOPHENYL)-1H-PYRAZOLE
- Synonyms
- 1-(3-bromophenyl)pyrazole;1-(3-BROMOPHENYL)-1H-PYRAZOLE;3-(1H-Pyrazol-1-yl)bromobenzene;1H-Pyrazole, 1-(3-bromophenyl)-;1-(3-Bromophenyl)-1H-pyrazole97%;1-(3-Bromophenyl)-1H-pyrazole - [B92957];1-(3-Bromophenyl)-1H-pyrazole, CAS 294877-33-1
- CBNumber
- CB6131193
- Molecular Formula
- C9H7BrN2
- Formula Weight
- 223.07
- MOL File
- 294877-33-1.mol
1-(3-BROMOPHENYL)-1H-PYRAZOLE Property
- storage temp.
- Room temperature.
- Appearance
- Light yellow to yellow Solid
Safety
- Hazard Note
- Harmful
- HazardClass
- IRRITANT
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B694993
- Product name
- 1-(3-Bromophenyl)-1H-pyrazole
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B694993
- Product name
- 1-(3-Bromophenyl)-1H-pyrazole
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 058797
- Product name
- 1-(3-Bromo-phenyl)-1H-pyrazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $171
- Updated
- 2021/12/16
- Product number
- OR1418
- Product name
- 1-(3-Bromophenyl)-1H-pyrazole
- Purity
- 97%
- Packaging
- 5g
- Price
- $122
- Updated
- 2021/12/16
- Product number
- 3H32-9-P6
- Product name
- 1-(3-Bromophenyl)-1H-pyrazole
- Purity
- 97%
- Packaging
- 5G
- Price
- $135
- Updated
- 2021/12/16
1-(3-BROMOPHENYL)-1H-PYRAZOLE Chemical Properties,Usage,Production
Synthesis
288-13-1
591-18-4
294877-33-1
1. To a 1 L round bottom flask was added a dioxane solution (400 mL) of 1-bromo-3-iodobenzene (18.20 g, 64.3 mmol), 1H-pyrazole (4.38 g, 64.3 mmol), and (1S,2S)-cyclohexane-1,2-diamine (1.5 g, 12.9 mmol). 2. cuprous iodide (I) (0.613 g, 3.22 mmol) and potassium carbonate (17.78 g, 129 mmol) were added and the reaction mixture was stirred under reflux conditions for 19 hours. 3. After completion of the reaction, the crude mixture was filtered through a diatomaceous earth pad. 4. The filtrate was diluted with 400 mL of dichloromethane and washed with deionized water. 5. The organic layer was separated, concentrated and purified by silica gel column chromatography using a hexane solution of 5% ethyl acetate as eluent to give 7.3 g (51% yield) of 1-(3-bromophenyl)-1H-pyrazole as a white solid. 6. Subsequently, the synthesis of N-(3-(1H-pyrazol-1-yl)phenyl)-3-(1-(2,6-dimethylphenyl)-1H-imidazol-4-yl)-N-phenylaniline was carried out.
References
[1] Patent: KR101897044, 2018, B1. Location in patent: Paragraph 0444-0445; 0448-0450
[2] Patent: EP2574613, 2013, A1. Location in patent: Paragraph 0144
1-(3-BROMOPHENYL)-1H-PYRAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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