9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL
- Product Name
- 9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL
- CAS No.
- 124027-47-0
- Chemical Name
- 9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL
- Synonyms
- PD-131620;1-Hydroxytacrine;9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL
- CBNumber
- CB6131870
- Molecular Formula
- C13H14N2O
- Formula Weight
- 214.26
- MOL File
- 124027-47-0.mol
9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL Property
- Melting point:
- 245℃
- Boiling point:
- 450.3±45.0 °C(Predicted)
- Density
- 1.315±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 13.47±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CD11318925
- Product name
- Velnacrine
- Purity
- 95+%
- Packaging
- 25mg
- Price
- $110
- Updated
- 2026/05/27
- Product number
- CD11318925
- Product name
- Velnacrine
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $221
- Updated
- 2026/05/27
- Product number
- CD11318925
- Product name
- Velnacrine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $353
- Updated
- 2026/05/27
- Product number
- CD11318925
- Product name
- Velnacrine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $882
- Updated
- 2026/05/27
- Product number
- BD-A134094
- Product name
- Velnacrine
- Purity
- 95%
- Packaging
- 50mg
- Price
- $134
- Updated
- 2026/05/26
9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL Chemical Properties,Usage,Production
Uses
Velnacrine (HP 029 free base) is an inhibitor for acetylcholinesterase (AChE), with an IC50 of 3.27 μM. Velnacrine reverses the Scopolamine (HY-N0296)-induced amnesia in rat models, and exhibits acute toxicity with LD50 of 65 mg/kg[1].
Definition
ChEBI: 9-amino-1,2,3,4-tetrahydroacridin-1-ol is a member of acridines.
IC 50
AChE: 3.27 μM (IC50)
References
[1] Tabarrini O, et al., Velnacrine thiaanalogues as potential agents for treating Alzheimer's disease. Bioorg Med Chem. 2001 Nov;9(11):2921-8. DOI:10.1016/s0968-0896(01)00171-7
9-AMINO-1,2,3,4-TETRAHYDRO-ACRIDIN-1-OL Preparation Products And Raw materials
Raw materials
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