ChemicalBook > CAS DataBase List > L 741626

L 741626

Product Name
L 741626
CAS No.
81226-60-0
Chemical Name
L 741626
Synonyms
3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole;4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL;4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-;receptor,selective,TNF-α,Inhibitor,dopamine,Dopamine Receptor,production,L-741626,L 741626,L741626,inhibit
CBNumber
CB61320787
Molecular Formula
C20H21ClN2O
Formula Weight
340.85
MOL File
81226-60-0.mol
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L 741626 Property

Boiling point:
548.8±50.0 °C(Predicted)
Density 
1.311±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: ≥20mg/mL
form 
powder
pka
13.87±0.20(Predicted)
color 
white to beige
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L135
Product name
L-741,626
Purity
≥98% (HPLC)
Packaging
10mg
Price
$162
Updated
2024/03/01
Sigma-Aldrich
Product number
L135
Product name
L-741,626
Purity
≥98% (HPLC)
Packaging
50mg
Price
$683
Updated
2024/03/01
Sigma-Aldrich
Product number
5.05879
Product name
L-741,626 - CAS 81226-60-0 - Calbiochem
Packaging
10mg
Price
$146
Updated
2022/05/15
Cayman Chemical
Product number
22354
Product name
L-741,626
Purity
≥98%
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
22354
Product name
L-741,626
Purity
≥98%
Packaging
10mg
Price
$116
Updated
2024/03/01
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L 741626 Chemical Properties,Usage,Production

Uses

L-741,626 is a selective D2DR inhibitor. Also, it is a G protein-coupled receptors antagonists and inverse agonists.

Uses

L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.

Definition

ChEBI: 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-4-piperidinol is a member of piperidines.

Hazard

A poison.

Biochem/physiol Actions

L-741,626 is a selective dopamine (D2) receptor antagonist.

storage

Store at RT

L 741626 Preparation Products And Raw materials

Raw materials

Preparation Products

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L 741626 Suppliers

AdooQ Bioscience CHINA
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81226-60-0, L 741626Related Search:


  • 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
  • 4-(4-CHLOROPHENYL)-1-(1H-INDOL-3-YL METHYL)PIPERIDIN-4-OL
  • receptor,selective,TNF-α,Inhibitor,dopamine,Dopamine Receptor,production,L-741626,L 741626,L741626,inhibit
  • 4-Piperidinol, 4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)-
  • 81226-60-0