ChemicalBook > CAS DataBase List > 3'-fluoro-3'-deoxyadenosine

3'-fluoro-3'-deoxyadenosine

Product Name
3'-fluoro-3'-deoxyadenosine
CAS No.
75059-22-2
Chemical Name
3'-fluoro-3'-deoxyadenosine
Synonyms
3'-F-3'-rA;3'-fluoro-3'-deoxyadenosine;3'-fluoro-3'-deoxyadenosine;3’-Deoxy-3’-fluoro adenosine;Adenosine, 3'-deoxy-3'-fluoro-;(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
CBNumber
CB61333211
Molecular Formula
C10H12FN5O3
Formula Weight
269.23
MOL File
75059-22-2.mol
More
Less

3'-fluoro-3'-deoxyadenosine Property

Melting point:
211-212 °C
Boiling point:
628.6±65.0 °C(Predicted)
Density 
2.01±0.1 g/cm3(Predicted)
pka
12.45±0.70(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C10H12FN5O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1
InChIKey
QCDAWXDDXYQEJJ-QYYRPYCUSA-N
SMILES
OC[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)[C@H](O)[C@@H]1F
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
D239975
Product name
3''-Deoxy-3''-fluoroadenosine
Packaging
10mg
Price
$175
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND15616
Product name
3'-Deoxy-3'-fluoroadenosine
Packaging
25mg
Price
$225
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND15616
Product name
3'-Deoxy-3'-fluoroadenosine
Packaging
5mg
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
ND15616
Product name
3'-Deoxy-3'-fluoroadenosine
Packaging
10mg
Price
$125
Updated
2021/12/16
AK Scientific
Product number
8706CA
Product name
3'-Fluoro-3'-deoxyadenosine
Packaging
5mg
Price
$151
Updated
2021/12/16
More
Less

3'-fluoro-3'-deoxyadenosine Chemical Properties,Usage,Production

Uses

3'-deoxy-3'-fluoroadenosine can be used as pharmaceutical intermediates for pharmaceutical experimental research.

Biological Activity

3'-Fluoro-3'-deoxyadenosine was active against a broad range of viruses, encompassing both DNA viruses [pox (vaccinia)], single-stranded (+) RNA viruses [picorna (polio, Coxsackie B), toga (sindbis, Semliki Forest)] and double-stranded RNA viruses (reo). Its antiviral activity spectrum, 3'-fluoro-3'-deoxyadenosine, clearly differed from those adenosine analogs known as inhibitors of S-adenosylhomocysteine hydrolase. 3'-Fluoro-3'-deoxyadenosine also proved effective in vivo in inhibiting tail lesion formation in mice inoculated intravenously with vaccinia virus[1].

References

[1] A. Van Aerschot. “Synthesis and antiviral activity evaluation of 3′-fluoro-3′-deoxyribonucleosides: broad-spectrum antiviral activity of 3′-fluoro-3′-deoxyadenosine.” Antiviral research 12 3 (1989): Pages 133-150.

3'-fluoro-3'-deoxyadenosine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3'-fluoro-3'-deoxyadenosine Suppliers

China 53 Switzerland 1 United Kingdom 2 United States 4 Global 60
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80

75059-22-2, 3'-fluoro-3'-deoxyadenosineRelated Search:


  • 3'-fluoro-3'-deoxyadenosine
  • (2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
  • 3'-F-3'-rA
  • Adenosine, 3'-deoxy-3'-fluoro-
  • 3'-fluoro-3'-deoxyadenosine
  • 3’-Deoxy-3’-fluoro adenosine
  • 75059-22-2