questin
- Product Name
- questin
- CAS No.
- 3774-64-9
- Chemical Name
- questin
- Synonyms
- questin;8-O-methylemodin;1,6-Dihydroxy-3-methyl-8-methoxy-9,10-anthraquinone;1,6-Dihydroxy-8-methoxy-3-methyl-9,10-anthracenedione;9,10-Anthracenedione, 1,6-dihydroxy-8-methoxy-3-methyl-
- CBNumber
- CB61336797
- Molecular Formula
- C16H12O5
- Formula Weight
- 284.26
- MOL File
- 3774-64-9.mol
questin Property
- Melting point:
- 301-303 °C
- Boiling point:
- 557.0±50.0 °C(Predicted)
- Density
- 1.448±0.06 g/cm3(Predicted)
- solubility
- Dichloromethane: soluble
DMSO: soluble
Ethanol: soluble
Methanol: soluble - form
- Solid
- pka
- 6.50±0.20(Predicted)
- color
- Yellow to orange
questin Chemical Properties,Usage,Production
Uses
Questin is an antibacterial agent isolated from marine Aspergillus flavipes. Questin exhibits antibacterial activity against V. harveyi, V. anguillarum, V. cholerae, and V. parahemolyticus with MIC values of 31.25 μg/mL, 62.5 μg/mL, 62.5 μg/mL, and 125 μg/mL[1].
Definition
ChEBI: Questin is a dihydroxyanthraquinone that is 1,6-dihyroxy-9,10-anthraquinone which is substituted by a methyl group at position 3 and a methoxy group at position 8. It is functionally related to an emodin. It is a conjugate acid of a questin-2-olate.
References
[1] Lei Guo, et al. Optimized production and isolation of antibacterial agent from marine Aspergillus flavipes against Vibrio harveyi. 3 Biotech. 2017 Dec;7(6):383. DOI:10.1007/s13205-017-1015-z
[2] SUNG-GYU CHOI. Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb.[J]. Natural Product Research, 2007, 21 6: 487-493. DOI: 10.1080/14786410601012265
[3] THIERRY GAUTHIER. Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells.[J]. PLoS ONE, 2012: e29906. DOI: 10.1371/journal.pone.0029906
[4] NIANZHEN LIU . Structurally diverse sesquiterpenoids and polyketides from a sponge-associated fungus Aspergillus sydowii SCSIO41301[J]. Fitoterapia, 2019, 135: Pages 27-32. DOI: 10.1016/j.fitote.2019.03.031
[5] NIRMALK. CHAUDHARY. Banksialactones and Banksiamarins: Isochromanones and Isocoumarins from an Australian Fungus, Aspergillus banksianus[J]. Journal of Natural Products , 2018, 81 7: 1517-1526. DOI: 10.1021/acs.jnatprod.7b00816
questin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from questin manufacturers
- Product
- Questin 3774-64-9
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-24
- Product
- questin 3774-64-9
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-29