marasmic acid
- Product Name
- marasmic acid
- CAS No.
- 2212-99-9
- Chemical Name
- marasmic acid
- Synonyms
- NSC318506;CCRIS 1701;NSC 318506;NSC-318506;marasmic acid;LACHNELLA FUNGUS;3H,6H-3a,8b-Methano-1H-indeno[4,5-c]furan-4-carboxaldehyde, 5a,7,8,8a-tetrahydro-3-hydroxy-7,7-dimethyl-1-oxo-, (3S,3aR,5aS,8aS,8bS)-
- CBNumber
- CB61339677
- Molecular Formula
- C15H18O4
- Formula Weight
- 262.3
- MOL File
- 2212-99-9.mol
marasmic acid Property
- Melting point:
- 173.5°C
- Boiling point:
- 339.23°C (rough estimate)
- Density
- 1.0721 (rough estimate)
- refractive index
- 1.4350 (estimate)
- pka
- 11.22±0.60(Predicted)
N-Bromosuccinimide Price
- Product number
- MTB0002160
- Product name
- MARASMIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.93
- Updated
- 2021/12/16
marasmic acid Chemical Properties,Usage,Production
Uses
Marasmic acid is a sesquiterpenoid with unsaturated dialdehyde functionality, first isolated from the Basidiomycete Marasmus conigenus. Marasmic acid has antibacterial, antifungal, cytotoxic and mutagenic activities, and its broad-spectrum activity is related to the α,β-unsaturated aldehyde group. However, its detailed biological mechanism of action has not been clarified. Previous studies have suggested that marasmic acid may exert its effects by reacting with endogenous nucleophiles or forming pyrrole derivatives. This study found that marasmic acid interferes with the membrane sensor histidine kinase MoSln1p of M. oryzae, superactivates the HOG pathway and causes cell death, indicating that its mechanism of action is different from other unsaturated dialdehyde sesquiterpenoids.
References
[1] Hog1p activation by marasmic acid through inhibition of the histidine kinase Sln1p
marasmic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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