11β-Hydroxyandrost-4-ene-3,17-dione
- Product Name
- 11β-Hydroxyandrost-4-ene-3,17-dione
- CAS No.
- 382-44-5
- Chemical Name
- 11β-Hydroxyandrost-4-ene-3,17-dione
- Synonyms
- u 2826;-dione;diol-d10;14αDecadiene;(17R)-4’4-Androsten-11;H)-furan]-3,3’Cortisone Impurity 1;Anthraceneacetic Acid
- CBNumber
- CB6136789
- Molecular Formula
- C19H26O3
- Formula Weight
- 302.41
- MOL File
- 382-44-5.mol
11β-Hydroxyandrost-4-ene-3,17-dione Property
- Melting point:
- 197-199℃
- Boiling point:
- 475.3±45.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 250 mg/mL (826.69 mM)
- form
- A crystalline solid
- pka
- 14.49±0.60(Predicted)
- color
- White to off-white
- InChI
- InChI=1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1
- InChIKey
- WSCUHXPGYUMQEX-KCZNZURUSA-N
- SMILES
- C1[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]2(C)[C@@]3([H])CCC2=O)=CC(=O)C1
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- A3009
- Product name
- 4-Androsten-11β-ol-3,17-dione
- Packaging
- 10mg
- Price
- $94.5
- Updated
- 2025/07/31
- Product number
- A3009
- Product name
- 4-Androsten-11β-ol-3,17-dione
- Packaging
- 100mg
- Price
- $419
- Updated
- 2025/07/31
- Product number
- Y2084
- Product name
- 4-Androsten-11beta-ol-3,17-dione
- Packaging
- 100mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- FA64923
- Product name
- 4-Androsten-11beta-ol-3,17-dione
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FA64923
- Product name
- 4-Androsten-11beta-ol-3,17-dione
- Packaging
- 500mg
- Price
- $187.5
- Updated
- 2021/12/16
11β-Hydroxyandrost-4-ene-3,17-dione Chemical Properties,Usage,Production
Uses
4-Androsten-11β-ol-3,17-dione is a steroid hormone. An analog of Androstenedione (A637550).
Definition
ChEBI: 11beta-hydroxyandrost-4-ene-3,17-dione is an 11beta-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a human metabolite and a mouse metabolite.
Biochem/physiol Actions
11β-Hydroxy-4-androstene-3,17-dione is a naturally occurring steroid that is primarily, if not strictly, produced in adrenal tissue. In diseases such as Cushing′s syndrome, adrenal-originated hyperandrogenism, and congenital adrenal hyperplasia, plasma 11β levels are very high. Plasma 11β concentration is very low in congenital 11-hydroxylase deficiency and adrenal insufficiency.
in vivo
The plasma concentration of 11-Beta-hydroxyandrostenedione (11beta-hydroxy-4-androstene-3,17-dione) is very high in 21-hydroxylase deficiency, Cushing's syndrome, and hyperandrogenism of adrenal origin, and very low in congenital 11-hydroxylase deficiency and adrenal insufficiency. Thus, when plasma 4-androstenedione is elevated, it is useful to measure the plasma 11-Beta-hydroxyandrostenedione level in order to determine the adrenal or ovarian origin of the hyperandrogenism[1].
IC 50
Human Endogenous Metabolite
11β-Hydroxyandrost-4-ene-3,17-dione Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 11β-Hydroxyandrost-4-ene-3,17-dione manufacturers
- Product
- 4-Androsten-11beta-ol-3,17-dione 382-44-5
- Price
- US $750.00/mg
- Min. Order
- 1mg
- Purity
- 98
- Supply Ability
- 1 Kg
- Release date
- 2025-09-12
- Product
- 4-ANDROSTEN-11BETA-OL-3,17-DIONE 382-44-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100 kg
- Release date
- 2020-01-10