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JACOLINE

Product Name
JACOLINE
CAS No.
480-76-2
Chemical Name
JACOLINE
Synonyms
Jacolin;JACOLINE;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
CBNumber
CB61438381
Molecular Formula
C18H27NO7
Formula Weight
369.41
MOL File
480-76-2.mol
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JACOLINE Property

Melting point:
221°C
Boiling point:
583.5±50.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
pka
12.40±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
J210403
Product name
Jacoline
Packaging
2.5mg
Price
$2640
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
1mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
2mg
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0001950
Product name
JACOLINE
Purity
95.00%
Packaging
5MG
Price
$505.59
Updated
2021/12/16
Biosynth Carbosynth
Product number
XJ161762
Product name
Jacoline
Packaging
5mg
Price
$750
Updated
2021/12/16
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JACOLINE Chemical Properties,Usage,Production

Description

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.

Uses

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).

References

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)

JACOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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JACOLINE Suppliers

China 15 United Kingdom 1 United States 2 Global 18
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
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sales@reading-chemicals.com
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China
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15178
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58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
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+86-27-84254680
Email
aileen@chemfaces.com
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China
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7059
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Biyu Biotechnology (Shanghai) Co., ltd
Tel
021-26018599
Country
China
ProdList
270
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56
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
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60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
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China
ProdList
131957
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58
Shenzhen Regent Biochemical Technology Co., Ltd.
Tel
0755-0755-85201366 18938635012
Fax
0755-85201366
Email
sales@regentsciences.com
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China
ProdList
9355
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58
Nanjing Digger Medical Technology Co. Ltd.
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025-025-51191215 18013836722
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025-51191215
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2399235533@qq.com
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China
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4933
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58
Wuxi Helen Biotechnology Co., Ltd.,
Tel
0510-85629785 18013409632
Fax
0510-85625359
Email
sales@reading-chemicals.com
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China
ProdList
14081
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58
cjbscvictory
Tel
13348960310 13348960310
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3003867561@qq.com
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China
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TCI (Shanghai) Chemical Trading Co., Ltd.
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021-021-61109150
Fax
021-61105897
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sales@tcisct.com
Country
China
ProdList
31121
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58

480-76-2, JACOLINERelated Search:

retronecine 3-BUTOXYPYRROLIDINE (2S)-2,3-Dihydroxy-2-methyl-propanoic Acid Methyl Ester 90% (R)-ETHYL 3-METHYL-2-HYDROXYBUTANOATE 2,3,5,7A-TETRAHYDRO-1H-PYRROLIZINE (S)-ALLYL LACTATE JACOLINE DL-LEUCIC ACID ISOPROPYL ESTER 3-PROPOXYPYRROLIDINE

  • JACOLINE
  • Jacolin
  • [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
  • (20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione
  • 480-76-2