magnolamine
- Product Name
- magnolamine
- CAS No.
- 573-73-9
- Chemical Name
- magnolamine
- Synonyms
- magnolamine;(1S)-1,2,3,4-Tetrahydro-1-[[4-[4-hydroxy-5-methoxy-2-[[(1S)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methylisoquinolin-7-ol;7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[[4-[4-hydroxy-5-methoxy-2-[[(1S)-1,2,3,4-tetrahydro-7-hydroxy-6-methoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenyl]methyl]-6-methoxy-2-methyl-, (1S)-
- CBNumber
- CB61480618
- Molecular Formula
- C37H42N2O7
- Formula Weight
- 626.74
- MOL File
- 573-73-9.mol
magnolamine Property
- Melting point:
- 117-9°C
- Boiling point:
- 768.0±60.0 °C(Predicted)
- Density
- 1.254±0.06 g/cm3(Predicted)
- pka
- 10.12±0.25(Predicted)
magnolamine Chemical Properties,Usage,Production
Description
This bisbenzylisoquinoline alkaloid is found in the benzene-soluble portion of the total alkaloids extracted from Magnolia fuscata. When recrystallized from C6H6 it yields fine, colourless needles, soluble in alkalies, CHC13 and EtOH. It is dextrorotatory with [α]D + 111.6° and yields a crystalline picrate, m.p. 142- SoC (dec.); a picrolonate, m.p. 163-4°C and a tetramethyl ether, m.p. lSI-2°C. The latter may be oxidized by KMn04 in Me2CO to give 1-keto-6:7-dimethoxy- 2-methyltetrahydroisoquinoline, m.p. 124-5°C and magnolaminic acid, C16H1407, m.p. 280-loC. The alkaloid acts as a cardiac depressant at between 10 to 500 parts per million.
References
Proskurnina, Orekhov., Bull. Soc. Chim., 5, 1357 (1938) Proskurnina., J. Gen. Chem. USSR., 16, 129 (1946) Tomita.,J. Pharm. Soc., Japan, 1075 (1951) Tomita, Kugo., Chem. Abstr., SO, 1056 (1956) Pharmacology: Buchi., Schweiz. Apoth. Zeit., 83, 198 (1945)
magnolamine Preparation Products And Raw materials
Raw materials
Preparation Products
magnolamine Suppliers
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- Country
- China
- ProdList
- 21633
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- 55