2,4(1H,3H)-Quinazolinedione, 6-methyl-
- Product Name
- 2,4(1H,3H)-Quinazolinedione, 6-methyl-
- CAS No.
- 62484-16-6
- Chemical Name
- 2,4(1H,3H)-Quinazolinedione, 6-methyl-
- Synonyms
- NSC 338219;6-Methylquinazoline-2,4-diol;6-methyl-1H-quinazoline-2,4-dione;6-Methyl-1H-quinazoline-2,4-quinone;6-Methyl-2,4(1H,3H)-quinazolinedione;6-Methylquinazoline-2,4(1H,3H)-dione;2,4(1H,3H)-Quinazolinedione, 6-methyl-;6-Methylquinazoline-2,4(1H,3H)-dione,97%;6-Methyl-1,2,3,4-tetrahydro-2,4-quinazolinedione;6-Methyl-1,2,3,4-tetrahydroquinazoline-2,4-dione
- CBNumber
- CB61509227
- Molecular Formula
- C9H8N2O2
- Formula Weight
- 176.17
- MOL File
- 62484-16-6.mol
2,4(1H,3H)-Quinazolinedione, 6-methyl- Property
- Melting point:
- 314-316℃
- Density
- 1.280±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 11.19±0.20(Predicted)
- form
- Solid
- color
- Off-white
- InChI
- InChI=1S/C9H8N2O2/c1-5-2-3-7-6(4-5)8(12)11-9(13)10-7/h2-4H,1H3,(H2,10,11,12,13)
- InChIKey
- OXVPNGBFUAIXTE-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(C)C=C2)C(=O)NC1=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M341858
- Product name
- 6-Methylquinazoline-2,4(1H,3H)-dione
- Packaging
- 500mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- CHM0311799
- Product name
- 2,4(1H,3H)-QUINAZOLINEDIONE, 6-METHYL-
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.46
- Updated
- 2021/12/16
- Product number
- 4H48-1-MV
- Product name
- 6-Methyl-1,2,3,4-tetrahydroquinazoline-2,4-dione
- Packaging
- 500mg
- Price
- $623
- Updated
- 2021/12/16
- Product number
- X6087
- Product name
- 6-Methyl-1H-quinazoline-2,4-quinone
- Packaging
- 25g
- Price
- $2295
- Updated
- 2021/12/16
- Product number
- 089533
- Product name
- 6-Methylquinazoline-2,4(1H,3H)-dione
- Packaging
- 25g
- Price
- $3860
- Updated
- 2021/12/16
2,4(1H,3H)-Quinazolinedione, 6-methyl- Chemical Properties,Usage,Production
Synthesis
590-28-3
2941-78-8
62484-16-6
Synthesis of 6-methylquinazoline-2,4-dione: 2-amino-5-methylbenzoic acid (0.758 g, 5 mmol) and potassium cyanate (0.673 g, 8.3 mmol) were suspended in water (20 mL) followed by addition of acetic acid (0.5 mL). The reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the resulting white solid product was collected by vacuum filtration, washed with water and dried under vacuum to afford 6-methylquinazoline-2,4-dione (0.736 g, 84% yield). The structure of the product was confirmed by 1H NMR (DMSO-d6): δ 9.90 (br s, 1H), 8.27 (d, J = 8.4 Hz, 1H), 7.70 (d, J = 1.8 Hz, 1H), 7.29 (dd, J = 2.4, 8.7 Hz, 1H), 6.50 (br s, 1H), 2.25 (s, 3H).
References
[1] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 1, p. 119 - 132
[2] Patent: WO2005/3100, 2005, A2. Location in patent: Page 185
[3] Patent: WO2006/74187, 2006, A2. Location in patent: Page/Page column 49
[4] Patent: WO2008/16666, 2008, A2. Location in patent: Page/Page column 49
[5] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 3, p. 308 - 312
2,4(1H,3H)-Quinazolinedione, 6-methyl- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,4(1H,3H)-Quinazolinedione, 6-methyl- manufacturers
- Product
- 2,4(1H,3H)-Quinazolinedione, 6-methyl- 62484-16-6
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-14