ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE
- Product Name
- ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE
- CAS No.
- 6214-46-6
- Chemical Name
- ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE
- Synonyms
- ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE;ethyl 2-(6-oxo-1H-pyrimidin-5-yl)acetate;4-Hydroxy-5-pyrimidineacetic acid ethyl ester;ethyl 2-(6-oxo-1,6-dihydropyriMidin-5-yl)acetate;2-(6-oxo-1H-pyrimidin-5-yl)acetic acid ethyl ester;5-Pyrimidineaceticacid, 3,4-dihydro-4-oxo-, ethyl ester;ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE ISO 9001:2015 REACH
- CBNumber
- CB61511592
- Molecular Formula
- C8H10N2O3
- Formula Weight
- 182.18
- MOL File
- 6214-46-6.mol
ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE Property
- Melting point:
- 155-156 °C
- Density
- 1.27±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 8.62±0.40(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933599590
N-Bromosuccinimide Price
- Product number
- E945793
- Product name
- Ethyl2-(4-hydroxypyrimidin-5-yl)acetate
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- OR953529
- Product name
- Ethyl2-(4-hydroxypyrimidin-5-yl)acetate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $185
- Updated
- 2021/12/16
- Product number
- OR953529
- Product name
- Ethyl2-(4-hydroxypyrimidin-5-yl)acetate
- Purity
- 95%
- Packaging
- 1g
- Price
- $470
- Updated
- 2021/12/16
- Product number
- CHM0392273
- Product name
- ETHYL-2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.49
- Updated
- 2021/12/16
- Product number
- 9334AB
- Product name
- Ethyl2-(4-hydroxypyrimidin-5-yl)acetate
- Packaging
- 5g
- Price
- $620
- Updated
- 2021/12/16
ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE Chemical Properties,Usage,Production
Synthesis
3473-63-0
5472-38-8
6214-46-6
The ethanolic solution of sodium ethoxide was cooled to 0 °C under argon protection. Under continuous stirring, diethyl 2-formylsuccinate was slowly added. after 5 minutes, the corresponding formamidine acetate was added drop by drop while maintaining the condition of 0°C. Subsequently, the reaction mixture was warmed up to room temperature and stirred continuously for 3 days. After completion of the reaction, 5% aqueous hydrogen chloride solution was added and stirring was continued for 30 minutes. After addition of appropriate amount of water, ethanol was removed by distillation under reduced pressure at 30 °C. Finally, the precipitate was collected by filtration to afford the target product ethyl 4-hydroxy-5-pyrimidineacetate (Compound 1, where X = H, Me, Ph, SMe; Y = H, R1 = Et).
References
[1] Monatshefte fur Chemie, 2016, vol. 147, # 4, p. 767 - 773
ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE manufacturers
- Product
- ETHYL2-(4-HYDROXYPYRIMIDIN-5-YL)ACETATE 6214-46-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-10