N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE

Product Name: N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE
CAS No.: 76315-01-0
Chemical Name: N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE
Synonyms: OTAVA-BB 1403921;N-Boc-N-benzyl-glycine;N-Benzyl-N-Cbz-glycine;N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE;N-α-(t-Butoxycarbonyl)-N-α-benzylglycine;2-(BENZYL(TERT-BUTOXYCARBONYL)AMINO)ACETIC ACID;(N-benzyl-N-tert-butoxycarbonyl)aminoacetic acid;2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid 95+%;Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-(phenylmethyl)-;2-[benzyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetic acid
CBNumber: CB61518203
Molecular Formula: C14H19NO4
Formula Weight: 265.3
MOL File: 76315-01-0.mol

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N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE Property

Boiling point:: 409.5±34.0 °C(Predicted)
Density: 1.170±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.01±0.10(Predicted)
form: Solid

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Safety

HazardClass: IRRITANT
HS Code: 2921490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: W8324
Product name: 2-(Benzyl(tert-butoxycarbonyl)amino)aceticacid
Packaging: 250mg
Price: $85
Updated: 2021/12/16

Activate Scientific

Product number: AS85392
Product name: N-Boc-N-benzyl-glycine
Purity: 95+%
Packaging: 1g
Price: $139
Updated: 2021/12/16

Activate Scientific

Product number: AS85392
Product name: N-Boc-N-benzyl-glycine
Purity: 95+%
Packaging: 5G
Price: $401
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4658-1-75
Product name: 2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid
Packaging: 1g
Price: $488
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0315818
Product name: 2-(BENZYL(TERTBUTOXY CARBONYL)AMINO)ACETIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $498.28
Updated: 2021/12/16

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N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE Chemical Properties,Usage,Production

Uses

2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid is a Glycine.html" class="link-product" target="_blank">Glycine (HY-Y0966) derivative[1].

Synthesis

24424-99-5

7689-50-1

76315-01-0

N-benzylglycine hydrochloride (3 g, 14.88 mmol) and di-tert-butyl dicarbonate (3.25 g, 14.88 mmol) were reacted in dichloromethane (40 mL). Triethylamine (6.22 mL, 44.6 mmol) was added to the reaction system and stirred at room temperature for 6 days. Upon completion of the reaction, the reaction mixture was partitioned with dichloromethane and dilute hydrochloric acid and the organic phase was extracted with dichloromethane (3 x 20 mL). The organic layers were combined, washed sequentially with water (20 mL) and brine (20 mL) and dried over anhydrous magnesium sulfate. Concentration gave the target product N-BOC-N-benzylglycine (5 g, 125% yield) as a clear, colorless oil containing a small amount of triethylamine hydrochloride impurity. The product was characterized by 1H NMR (400 MHz, CDCl3): δ1.38-1.46 (d, 9H), 3.71 (s, 1H), 3.86 (s, 1H), 4.54 (d, J=12.38Hz, 2H), 7.07-7.37 (m, 5H). The product does not require further purification and can be used directly in the next reaction.

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE Suppliers

China 39 India 1 Japan 1 United Kingdom 2 United States 6 Global 49

J & K SCIENTIFIC LTD.

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View Lastest Price from N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE manufacturers

Career Henan Chemical Co

Product: N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE 76315-01-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-24

76315-01-0, N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINERelated Search:

BOC-7-HYDROXY-TIC-OH tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate BOC-7-HYDROXY-D-TIC-OH 1,3-DIHYDRO-ISOINDOLE-1,2-DICARBOXYLIC ACID 2-TERT-BUTYL ESTER (5S)-N-(tert-Butoxycarbonyl)-3,4,5,6-tetrahydro-5-phenyl-4(H)-1,4-oxazin-2-one BOC-(4S,2RS)-2-PHENYLTHIAZOLIDINE-4-CARBOXYLIC ACID BOC-DL-5-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID, 98 6-PHENYL-PIPERIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE (2S,5R)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID (2R,5S)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID BOC-D-TIC-OH (5R)-N-(TERT-BUTOXYCARBONYL)-3,4,5,6-TETRAHYDRO-5-PHENYL-4(H)-1,4-OXAZIN-2-ONE 3-(TERT-BUTOXYCARBONYL)-2-(4-METHYLPHENYL)-1,3-THIAZOLANE-4-CARBOXYLIC ACID N-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYL 6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE N-BOC-(S)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-CARBOXYLIC ACID HCL

N-BENZYL-N-(TERT-BUTOXYCARBONYL)GLYCINE

2-(BENZYL(TERT-BUTOXYCARBONYL)AMINO)ACETIC ACID

OTAVA-BB 1403921

Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-(phenylmethyl)-

N-Boc-N-benzyl-glycine

tert-Butyl N-(2-hydroxy-2-oxoethyl)-N-(phenylmethyl)carbamate

(N-benzyl-N-tert-butoxycarbonyl)aminoacetic acid

2-(Benzyl(tert-butoxycarbonyl)amino)acetic acid 95+%

N-α-(t-Butoxycarbonyl)-N-α-benzylglycine

2-[benzyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]acetic acid

N-Benzyl-N-Cbz-glycine

76315-01-0