5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
- Product Name
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
- CAS No.
- 888504-28-7
- Chemical Name
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
- Synonyms
- 5-Methyl-;Raltegravir Oxadiazole Impurity;5-Methyl-1,3,4-oxadiazole-2-carboxylate;4-oxadiazole-2-carboxylic acid potassium salt;5-methyl-1,3,4-oxadiazole-2-carboxylic acid potassium;potassiuM 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid;5-Methyl-1,3,4-oxadiazole-2-carboxylate,potassium salt;Potassium salt, 5-methyl-1,3, 4-oxadiazole-2-carboxylate;5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt;7,8-difluoro-6,11-dihydro-dibenzo [b, e] thieno-11-alcohol
- CBNumber
- CB61518647
- Molecular Formula
- C4H3KN2O3
- Formula Weight
- 166.18
- MOL File
- 888504-28-7.mol
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Property
- Melting point:
- 258.3 °C (decomp)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Water
- form
- Solid
- color
- Off-White
- InChI
- InChI=1S/C4H4N2O3.K/c1-2-5-6-3(9-2)4(7)8;/h1H3,(H,7,8);/q;+1/p-1
- InChIKey
- BRHMYHXNUGVBCU-UHFFFAOYSA-M
- SMILES
- C1(C(=O)[O-])OC(C)=NN=1.[K+]
Safety
- WGK Germany
- 3
- HS Code
- 2918.99.4700
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P281Use personal protective equipment as required.
P308+P313IF exposed or concerned: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- P2220
- Product name
- Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 200mg
- Price
- $114
- Updated
- 2025/07/31
- Product number
- P2220
- Product name
- Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $355
- Updated
- 2025/07/31
- Product number
- 284616
- Product name
- 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt
- Packaging
- 5g
- Price
- $326
- Updated
- 2021/12/16
- Product number
- M320610
- Product name
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 090280
- Product name
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acidpotassium salt
- Purity
- 95+%
- Packaging
- 25g
- Price
- $215
- Updated
- 2021/12/16
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
An intermediate in the preparation of HIV-integrase inhibitors.
Synthesis
37641-36-4
888504-28-7
Synthesis of potassium 5-methyl-1,3,4-oxadiazole-2-carboxylate (19b): potassium triethylsilanolate (411 mg, 3.20 mmol) was suspended in ethyl ether at room temperature and stirred to form a slurry. Subsequently, ethyl 5-methyl-1,3,4-oxadiazole-2-carboxylate (0.50 g, 3.20 mmol) was added at once. The reaction immediately produced a precipitate, which changed color from white to off-white. The precipitate was separated by filtration, washed with ether and dried to give the title compound as an off-white solid (580 mg, quantitative yield).1H NMR (300 MHz, CDCl3): δ 2.61 (3H, s). 13C NMR (75 MHz, D2O): δ 166.7, 161.3, 159.3, 10.4.
References
[1] Patent: US2009/35324, 2009, A1. Location in patent: Page/Page column 12
[2] Patent: WO2016/127859, 2016, A1. Location in patent: Paragraph 00194
[3] Patent: CN106349233, 2017, A. Location in patent: Paragraph 0243; 0274; 0275; 0276
[4] Patent: WO2006/60711, 2006, A2. Location in patent: Page/Page column 30-31
[5] Patent: WO2006/60731, 2006, A2. Location in patent: Page/Page column 35-36
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Preparation Products And Raw materials
Raw materials
Preparation Products
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Suppliers
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- info@pschemicals.com
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- The Netherlands
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View Lastest Price from 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt manufacturers
- Product
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt 888504-28-7
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-12
- Product
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt 888504-28-7
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-08
- Product
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt 888504-28-7
- Price
- US $10.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-28