(6-Trifluoromethyl-pyridin-2-yl)-acetic acid

Product Name: (6-Trifluoromethyl-pyridin-2-yl)-acetic acid
CAS No.: 1000565-32-1
Chemical Name: (6-Trifluoromethyl-pyridin-2-yl)-acetic acid
Synonyms: RARECHEM AL MS 0229;2-(6-(Trifluoromethyl);6-(Trifluoromethyl)-2-pyridineacetic acid;6-(Trifluoromethyl)pyridine-2-acetic acid;2-(Trifluoromethyl)pyridine-6-acetic acid;2-pyridineacetic acid, 6-(trifluoromethyl)-;2-[6-(Trifluoromethyl)-2-pyridyl]acetic Acid;(6-Trifluoromethyl-pyridin-2-yl)-acetic acid;2-(6-(TRIFLUOROMETHYL)PYRIDIN-2-YL)ACETIC ACID;2-(6-(trifluoromethyl)pyridine-2-yl)acetic acid
CBNumber: CB61554166
Molecular Formula: C8H6F3NO2
Formula Weight: 205.13
MOL File: 1000565-32-1.mol

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(6-Trifluoromethyl-pyridin-2-yl)-acetic acid Property

Boiling point:: 250.8±35.0 °C(Predicted)
Density: 1.428±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka: 3.78±0.10(Predicted)

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T896893
Product name: 2-(6-(Trifluoromethyl)pyridin-2-yl)aceticAcid
Packaging: 500mg
Price: $925
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0049800
Product name: (6-TRIFLUOROMETHYL-PYRIDIN-2-YL)-ACETIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $501.17
Updated: 2021/12/16

Chemenu

Product number: CM277032
Product name: 2-(6-(Trifluoromethyl)pyridin-2-yl)aceticacid
Purity: 95%
Packaging: 1g
Price: $572
Updated: 2021/12/16

Crysdot

Product number: CD11370953
Product name: 2-(6-(Trifluoromethyl)pyridin-2-yl)aceticacid
Purity: 95+%
Packaging: 1g
Price: $576
Updated: 2021/12/16

Chemenu

Product number: CM277032
Product name: 2-(6-(Trifluoromethyl)pyridin-2-yl)aceticacid
Purity: 95%
Packaging: 5g
Price: $1683
Updated: 2021/12/16

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(6-Trifluoromethyl-pyridin-2-yl)-acetic acid Chemical Properties,Usage,Production

Uses

2-(6-(Trifluoromethyl)pyridin-2-yl)acetic Acid is used in preparation of Oxadiazole derivatives as microbicides.

Synthesis

1346541-27-2

1000565-32-1

Tert-butyl 6-(trifluoromethyl)-2-pyridylacetate (698 mg, 2.67 mmol) was used as a raw material and dissolved in dichloromethane (10 mL). Triethylsilane (1.067 mL, 6.68 mmol) and trifluoroacetic acid (2.68 mL, 34.7 mmol) were added dropwise via syringe at room temperature. The reaction mixture was stirred at room temperature overnight. After confirming good conversion of the reaction by LC-MS analysis, the reaction solution was concentrated to give a yellow oily substance. Diethyl ether (5 mL) was added to the oily material, no precipitate formation was observed, and the solution was subsequently concentrated to afford 2-(6-(trifluoromethyl)pyridin-2-yl)acetic acid (535 mg, 2.61 mmol, 98% yield) as a yellow oil, which solidified to a yellow solid upon standing.LC-MS (ES) m/z = 206 [M + H]+.1H NMR (400 MHz , DMSO-d6) δ ppm 3.89 (s, 2H), 7.70 (d, J = 7.83 Hz, 1H), 7.81 (d, J = 7.58 Hz, 1H), 7.97-8.16 (m, 1H), 12.26-12.88 (br.s., 1H).

References

[1] Patent: WO2011/119663, 2011, A1. Location in patent: Page/Page column 207

(6-Trifluoromethyl-pyridin-2-yl)-acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(6-Trifluoromethyl-pyridin-2-yl)-acetic acid Suppliers

China 48 India 1 United States 7 Global 56

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View Lastest Price from (6-Trifluoromethyl-pyridin-2-yl)-acetic acid manufacturers

Career Henan Chemical Co

Product: (6-Trifluoromethyl-pyridin-2-yl)-acetic acid 1000565-32-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-11

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1000565-32-1