N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE

Product Name: N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE
CAS No.: 80376-66-5
Chemical Name: N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE
Synonyms: meyers' tms form;N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE;N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine,98%;N'-tert-butyl-N-methyl-N-(trimethylsilylmethyl)methanimidamide;Methanimidamide, N'-(1,1-dimethylethyl)-N-methyl-N-[(trimethylsilyl)methyl]-;N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidineMeyers' TMS form reagent
CBNumber: CB6160140
Molecular Formula: C10H24N2Si
Formula Weight: 200.4
MOL File: 80376-66-5.mol

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N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Property

Boiling point:: 78-80 °C (7 mmHg)
refractive index: 1.45-1.452
storage temp.: 0-6°C

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22
Safety Statements: 36/37

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Hazard and Precautionary Statements (GHS)

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N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Chemical Properties,Usage,Production

Chemical Properties

CLEAR PALE YELLOW LIQUID

Uses

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE conveniently effects the transformation of ketones and aldehydes to homologated nitriles, amines, aldehydes, and ketones.

Synthesis

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE is easily synthesized by a two-step procedure (eq 1).1 Initially, the condensation of t-Butylamine with either N,N-Dimethylformamide or dimethylformamide dimethyl acetal cleanly affords N′-t-Butyl-N,N-dimethylformamidine. Subsequent lithiation and silylation with Chlorotrimethylsilane results in a 70% overall yield of the purified title reagent.

storage

The reagent should be handled in a fume hood. Refrigeration should be used for prolonged storage.

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE Suppliers

Belgium 1 Germany 1 Japan 1 United States 1 Global 4

Acros Organics

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3B Scientific Corporation

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Service Chemical Inc.

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Kanto Chemical Co., Inc.

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80376-66-5, N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINERelated Search:

(Trimethylsilyl)methylamine N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE N'-TERT-BUTYL-N,N-DIMETHYLFORMAMIDINE

meyers' tms form

N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidine,98%

N-Methyl-N-trimethylsilylmethyl-N'-tert-butylformamidineMeyers' TMS form reagent

N-METHYL-N-TRIMETHYLSILYLMETHYL-N'-TERT-BUTYLFORMAMIDINE

Methanimidamide, N'-(1,1-dimethylethyl)-N-methyl-N-[(trimethylsilyl)methyl]-

N'-tert-butyl-N-methyl-N-(trimethylsilylmethyl)methanimidamide

80376-66-5

C10H24N2Si