9(S)-HODE

Product Name: 9(S)-HODE
CAS No.: 73543-67-6
Chemical Name: 9(S)-HODE
Synonyms: 9-HOD;9(S)-HOD;9(S)-HODE;9(S)HODE,9(S) HODE;Alpha-dimorphecolic;9(S)-HODE MaxSpecStandard;NPDSHTNEKLQQIJ-UINYOVNOSA-N;9-Hydroxy-10t,12c-octadecadienoic acid;9(S)-HYDROXYOCTADECA-10E,12Z-DIENOIC ACID;9(S)-Hydroxy-10(E),12(Z)-ociadecadienoic acid
CBNumber: CB6162386
Molecular Formula: C18H32O3
Formula Weight: 296.44
MOL File: 73543-67-6.mol

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9(S)-HODE Property

Boiling point:: 416.1±33.0 °C(Predicted)
Density: 0.970±0.06 g/cm3(Predicted)
Flash point:: 14℃
storage temp.: -20°C
solubility: DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
pka: 4.78±0.10(Predicted)
form: ethanol solution (1 mg/mL)
color: colorless to light yellow

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Safety

Hazard Codes: F
Risk Statements: 11
Safety Statements: 7-16
RIDADR: UN1170 - class 3 - PG 2 - Ethanol, solution
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0503
Product name: 9(S)-HODE
Purity: ≥98% (HPLC)
Packaging: 100μg
Price: $160
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0503
Product name: 9(S)-HODE
Purity: ≥98% (HPLC)
Packaging: 500μg
Price: $637
Updated: 2025/07/31

Cayman Chemical

Product number: 38410
Product name: 9(S)-HODE
Purity: ≥98%
Packaging: 100μg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 23569
Product name: 9(S)-HODE MaxSpec? Standard
Purity: ≥95%
Packaging: 100μg
Price: $167
Updated: 2023/06/20

Cayman Chemical

Product number: 38410
Product name: 9(S)-HODE
Purity: ≥98%
Packaging: 500μg
Price: $521
Updated: 2024/03/01

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9(S)-HODE Chemical Properties,Usage,Production

Description

9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles.

Uses

9S-HODE (Alpha-dimorphecolic acid) is an octadecadienoic acid and the main active derivative of linoleic acid, which can reduce the viability of HL-60 cells and induce apoptosis. 9S-HODE is rich in lipid peroxidation (LPO) products and is almost an ideal marker for LPO[1][2].

Definition

ChEBI: A 9-HODE in which the 9-hydroxy group has S-stereochemistry.

IC 50

Human Endogenous Metabolite

References

[1] Liu S, et al. Linoleic acid derivatives target miR-361-3p/BTG2 to confer anticancer effects in acute myeloid leukemia. J Biochem Mol Toxicol. 2023 Nov;37(11):e23481. DOI:10.1002/jbt.23481
[2] Spiteller P, et al. 9-Hydroxy-10, 12-octadecadienoic acid (9-HODE) and 13-hydroxy-9, 11-octadecadienoic acid (13-HODE): excellent markers for lipid peroxidation[J]. Chemistry and Physics of Lipids, 1997, 89(2): 131-139.

9(S)-HODE Preparation Products And Raw materials

Raw materials

Preparation Products

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9(S)-HODE Suppliers

China 35 Germany 2 United Kingdom 2 United States 9 Global 48

Shanghai Aladdin Bio-Chem Technology Co.,LTD

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73543-67-6, 9(S)-HODERelated Search:

Undecenoic acid 9(S)-HPODE CIS-10,TRANS-12-CONJUGATEDLINOLEICACID 13(S)-HODE CHOLESTERYL ESTER 13(R)-HODE CHOLESTERYL ESTER (+/-)13-HODE CHOLESTERYL ESTER 9(R)-HODE CHOLESTERYL ESTER HODE,(+/-)13-HODE 13(S)-HODE-D4 9(S)-HODE (+/-)9-HODE 9(S)-HODE-D4 13(R)-HODE 9(S)-HODE CHOLESTERYL ESTER 13(S)-HODE-BIOTIN (+/-)9-HODE CHOLESTERYL ESTER Hydroxyoctadecadienoic Acid 13(S) (HODE) 9(R)-HODE

9(S)-HYDROXYOCTADECA-10E,12Z-DIENOIC ACID

9(S)-HYDROXY-10(E),12(Z)-OCTADECADIENOIC ACID

9(S)-HOD

9(S)-HODE

9(S)-Hydroxy-10(E),12(Z)-ociadecadienoic acid

(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid

Alpha-dimorphecolic

[10E,12Z,S,(+)]-9-Hydroxy-10,12-octadecadienoic acid

9-HOD

9-Hydroxy-10t,12c-octadecadienoic acid

NPDSHTNEKLQQIJ-UINYOVNOSA-N

9(S)-HODE MaxSpecStandard

10,12-Octadecadienoic acid, 9-hydroxy-, (9S,10E,12Z)-

9(S)HODE,9(S) HODE

73543-67-6