ChemicalBook > CAS DataBase List > N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE

N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE

Product Name
N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE
CAS No.
398138-28-8
Chemical Name
N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE
Synonyms
PGD2-EA;PROSTAGLANDIN D2 ETHANOLAMIDE;Prostaglandin D2 Ethanolamide MaxSpecStandard;Prostaglandin D2 Ethanolamide Lipid Maps MS Standard;N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE;Prosta-5,13-dien-1-amide, 9,15-dihydroxy-N-(2-hydroxyethyl)-11-oxo-, (5Z,9α,13E,15S)-;(Z)-N-(2-hydroxyethyl)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enamide
CBNumber
CB6174181
Molecular Formula
C22H37NO5
Formula Weight
395.54
MOL File
398138-28-8.mol
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N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE Property

Boiling point:
630.7±55.0 °C(Predicted)
Density 
1.134±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 8.3 mg/ml; DMSO: 8.3 mg/ml; Ethanol: 12.5 mg/ml; PBS (7.2): 2.5 mg/ml
pka
13.86±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
12012
Product name
Prostaglandin D2 Ethanolamide
Purity
≥96%
Packaging
1mg
Price
$89
Updated
2024/03/01
Cayman Chemical
Product number
12012
Product name
Prostaglandin D2 Ethanolamide
Purity
≥96%
Packaging
5mg
Price
$412
Updated
2024/03/01
Cayman Chemical
Product number
12012
Product name
Prostaglandin D2 Ethanolamide
Packaging
500μg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
10007203
Product name
Prostaglandin D2 Ethanolamide MaxSpec? Standard
Purity
≥95%
Packaging
100μg
Price
$115
Updated
2023/01/06
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N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE Chemical Properties,Usage,Production

Description

Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide; Item Nos. 90050 | 10007270) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines.

PGD2-EA MaxSpec® standard is a quantitative grade standard of PGD2-EA that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a deactivated glass ampule sealed under argon. The concentration was verified by comparison to an independently prepared calibration standard. The verified concentration is provided on the certificate of analysis. This PGD2-EA MaxSpec® standard is guaranteed to meet identity, purity, stability, and concentration specifications and is provided with a batch-specific certificate of analysis. Ongoing stability testing is performed to ensure the concentration remains accurate throughout the shelf life of the product. Note: The amount of solution added to the vial is in excess of the listed amount. Therefore, it is necessary to accurately measure volumes for preparation of calibration standards. Follow recommended storage and handling conditions to maintain product quality.

Definition

ChEBI: Prostaglandin D2 ethanolamide is an N-acylethanolamine resulting from the formal condensation of the carboxy group of prostaglandin D2 with the amino group of ethanolamine. It is a N-acylethanolamine and a monocarboxylic acid amide. It is functionally related to a prostaglandin D2.

N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE Suppliers

China 9 United States 1 Global 10
Shanghai Hongye Biotechnology Co. Ltd
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Hangzhou Synstar pharmaceutical Technology CO.,Ltd
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398138-28-8, N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDERelated Search:

N-[(2-HYDROXY-1-HYDROXYMETHYL)ETHYL]-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE

  • PGD2-EA
  • PROSTAGLANDIN D2 ETHANOLAMIDE
  • N-(2-HYDROXYETHYL)-11-OXO-9ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E-DIEN-1-AMIDE
  • (Z)-N-(2-hydroxyethyl)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enamide
  • Prostaglandin D2 Ethanolamide MaxSpecStandard
  • Prostaglandin D2 Ethanolamide Lipid Maps MS Standard
  • Prosta-5,13-dien-1-amide, 9,15-dihydroxy-N-(2-hydroxyethyl)-11-oxo-, (5Z,9α,13E,15S)-
  • 398138-28-8
  • C22H37NO5