N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide

Product Name: N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide
CAS No.: 336115-72-1
Chemical Name: N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide
Synonyms: CK0106023;N-[1-(3-Benzyl-7-chloro-4-oxo-quinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide;N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide;Benzamide, 4-bromo-N-[1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]propyl]-N-[3-(dimethylamino)propyl]-
CBNumber: CB61855423
Molecular Formula: C30H32BrClN4O2
Formula Weight: 595.96
MOL File: 336115-72-1.mol

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N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Property

Boiling point:: 717.0±70.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
pka: 9.33±0.28(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: HCH0316602
Product name: N-(1-(3-BENZYL-7-CHLORO-4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)PROPYL)-4-BROMO-N-(3-(DIMETHYLAMINO)PROPYL)BENZAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $501.22
Updated: 2021/12/16

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N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Chemical Properties,Usage,Production

Uses

CK0106023 is a potent and specific allosteric inhibitor of KSP with a Ki value of 12 nM, showing antitumor activity. CK0106023 causes mitotic arrest and growth inhibition in several tumor cell lines. CK0106023 exhibits antitumor activity in tumor-bearing mice[1][2].

References

[1] You-Ling Fan. End-capped polyarylene polyethers, articles made therefrom and process for preparing such polyarylene polyethers. EP0106023B1. 1988 March 30.
[2] Sakowicz R, et al. Antitumor activity of a kinesin inhibitor. Cancer Res. 2004 May 1;64(9):3276-80. DOI:10.1158/0008-5472.can-03-3839

N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide Suppliers

China 7 Germany 1 United States 2 Global 10

Shanghai Ennopharm Co., Ltd.

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336115-72-1, N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamideRelated Search:

N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide 3-BENZYL-2-PROPYL-3H-QUINAZOLIN-4-ONE 3-METHYL-2-(1-METHYLAMINOETHYL)-3H-QUINAZOLIN-4-ONE

N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-propyl]-4-bromo-N-(3-dimethylamino-propyl)-benzamide

CK0106023

N-[1-(3-Benzyl-7-chloro-4-oxo-quinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide

Benzamide, 4-bromo-N-[1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]propyl]-N-[3-(dimethylamino)propyl]-

336115-72-1

C30H32BrClN4O2