5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine

Product Name: 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine
CAS No.: 68892-41-1
Chemical Name: 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine
Synonyms: DMT-DG-IBU;ibu-dmt-dg;DMT-i-bu-dG;DMT-N-IB-DG;DMT-NIBU-DG;5'-DMT-ibu-dG;N2-iBu-DMT- dG;DMT-DG-(N-IBU);5'-ODMT N-iBu dG;5'-O-DMT-N2-ibu-dG
CBNumber: CB6192118
Molecular Formula: C35H37N5O7
Formula Weight: 639.7
MOL File: 68892-41-1.mol

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5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Property

Melting point:: ~150 °C (dec.)(lit.)
Boiling point:: 671.92°C (rough estimate)
Density: 1.2353 (rough estimate)
refractive index: 1.7500 (estimate)
storage temp.: Inert atmosphere,2-8°C
solubility: soluble in Methanol
form: powder to crystal
pka: 9.16±0.20(Predicted)
color: White
Water Solubility: 2.4mg/L at 20℃
InChIKey: RMQXDNUKLIDXOS-PTIWCXHYNA-N
SMILES: C(OC[C@@H]1[C@@H](O)C[C@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)O1)(C1=CC=CC=C1)(C1C=CC(OC)=CC=1)C1=CC=C(OC)C=C1 |&1:3,4,7,r|
LogP: 2.98 at 20℃
CAS DataBase Reference: 68892-41-1(CAS DataBase Reference)
EPA Substance Registry System: Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)- (68892-41-1)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 1-3-10
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Hazard statements

H302Harmful if swallowed

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: I0697
Product name: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
Purity: >99.0%(HPLC)
Packaging: 1g
Price: $37
Updated: 2024/03/01

TCI Chemical

Product number: I0697
Product name: N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine
Purity: >99.0%(HPLC)
Packaging: 5g
Price: $186
Updated: 2024/03/01

Cayman Chemical

Product number: 30472
Product name: N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
Packaging: 100mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 30472
Product name: N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
Packaging: 250mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 30472
Product name: N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine
Packaging: 50mg
Price: $32
Updated: 2024/03/01

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5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Chemical Properties,Usage,Production

Uses

N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine (5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine) can be used as fluorescent hydrogel with high intensity.

Flammability and Explosibility

Not classified

Synthesis

2N-Isobutyryl deoxyguanosine (B5-I) was dried by co-evaporation with dry pyridine three times. To a stirred suspension of dry (B5-I) (14.15 mmol) in pyridine (100 mL), a solution of dimetoxytrityl chloride (14.8 mmol) in pyridine (30 mL) was added dropwise over 60 min. The reaction mixture was left for 4 h at room temperature, cooled to 0 C. by immersion in an ice water bath, quenched with 5% NaHCO3 (100 mL), and extracted with ethyl acetate (3×100 mL). The organic fractions were pooled, dried over magnesium sulfate, and concentrated in a vacuum, and the residue was co-evaporated with toluene. The gum oil residue was dissolved in a minimum amount of methylenechloride and added dropwise to a mixture of ethyl and petroleum ether (2000 mL 75/25) with stirring. After 20 min, pure 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine precipitated from the solution and was filtered off and dried. Yield: 75%

5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Suppliers

Americas 1 Belgium 1 China 138 Europe 3 Germany 4 India 5 Japan 2 Slovakia 1 Switzerland 1 United Kingdom 7 United States 24 Global 187

Nanjing Youwei Biotechnology Co., Ltd

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View Lastest Price from 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine manufacturers

Shanghai Qyubiotech Co., Ltd.

Product: N2-iBu-DMT-dG 68892-41-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000kgs per Month
Release date: 2023-11-08

Zhejiang Hengkang Pharmaceutical Co., Ltd.

Product: iBu-DMT-dG 68892-41-1
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 500kg per month
Release date: 2022-11-25

SHANGHAI NOVRIBO BIOTECH

Product: 5'-DMT-iBu-dG; 5’-O-DMT-2’-Deoxy-N2-iBu-Guanosine 68892-41-1
Price: US $100.00/kg
Min. Order: 0.009999999776482582kg
Purity: 99%
Supply Ability: 5tons
Release date: 2023-03-21

68892-41-1, 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosineRelated Search:

5'-O-Dimethoxytrityl-deoxythymidine 5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine 2'-Deoxyguanosine N2-Isobutyryl-2'-deoxyguanosine Isobutyramide N2-ISOBUTYRYL-2'-DEOXYGUANOSINE DMT-dG(ib) Phosphoramidite 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE-3'-(METHYL-N,N-DIISOPROPYL)PHOSPHORAMIDITE 5'-O-(DIMETHOXYTRITYL)-8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE IBU-DMT-DEOXYGUANOSINE SUCCINIC ACID 5'-DMT-RIBO GUANOSINE (N-IBU) 2'-Deoxyguanosine monohydrate 5'-O-FDMT-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE CEP 3'-DMT-DG(IBU)-SUC-CPG 5'-DMT-DG(IBU)-SUC-CPG N2-(ISOBUTYRYL)-5'-O-(DIMETHOXYTRITYL)-2'-O-(T-BUTYLDIMETHYLSILYL)-GUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE 5'-DIMETHOXYTRITYL-N2-ISOBUTYRYL-2'-(2-METHOXYETHYL)GUANOSINE

5'-O-DIMETHOXYTRITYL-N-ISOBUTYRYL-DEOXYGUANOSINE

5'-O-(4,4'-DIMETHOXYTRITYL)-N2-ISOBUTYRYL-2'-DEOXYGUANOSINE

N(sup 2)-isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxygu

N-[9-[(2R,4S,5R)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide

2'-Deoxy-5'-O-(4,4'-dimethoxytrityl)-N-isobutyrylguanosine

5'-O-(4,4'-Dimethoxytrityl)-N-isobutyryl-2'-deoxyguanosine

N-[9-[5-O-(4,4'-Dimethoxytrityl)-2-deoxy-β-D-ribofuranosyl]-6-oxo-1,6-dihydro-9H-purine-2-yl]isobutyramide

DMT-i-bu-dG

5'-DMT-ibu-dG

5'-O-Dimethoxytrityl-N2-Isobutylryl-2'-deoxyguanosine

2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine

N2-iBu-DMT- dG

iBu-DMT-dG 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine

N<sup>2</sup>-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine, 98%

IBU-DMT-DEOXYGUANOSINE

DMT-DG-IBU

DMT-N-IB-DG

DMT-NIBU-DG

N2-ISOBUTYRYL-5'-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE

N2-ISOBUTYRYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE

N2-ISOBUTYROYL-5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE

guanosine,5’-o-[bis(4-methoxyphenyl)phenylmethyl]-2’-deoxy-n-(2-methyl-1-oxopr

5'-O-[bis(4-methoxyphenyl)benzyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)guanosine

DMT-DG-(N-IBU)

5'-O-Dimethylterephthalate-N-isobutyryl-2'-deoxyguanosine

5'-O-DIMETHOXYTRITYL-N-ISOBUTYRYL-DEOXYGUANOSINE(DMT-DG-IBU)

5'-O-Dimethoxytrityl-N-BenzoylDeoxycytidine

5''-O-(4,4''-Dimethoxytrityl)-N2-isobutyryl-2''-deoxyguanosine (synthetic)

ibu-dmt-dg

2'-Deoxy-5'-O-DMT-N2-Isobutyryl-D-guanosine

5''-O-DIMETHOXYTRITYL-N-ISO-BUTYRYLDEOXYGUANOSINE(DMT-BZ-DG)

Guanosine, 5'-O-[bis(4-methoxyphenyl) phenylmethyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)-

N2-iso-Butyroyl-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-guanosine

N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine&gt

5'-O-DMT-N2-ibu-dG

5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine USP/EP/BP

5’ O-DIMETHOXY-N-ISOBUTYRYLDEOXYGUANOSINE

TIANFU-CHEM 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine

5'-O-DMT-N2-isobutyryl-2'-deoxyguanosine

5'-O-DMT-2'-Deoxy-N2-iBu-Guanosine

5′-O-[Bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)guanosine

N-(9-((2S,4R,5S)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide

5'-ODMT N-iBu dG

5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine

N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine

5'-O-DMT-N2-ibu-dG

5'-O-DMT-N2-Isobutyryl-2'-Deoxyguanosine

5’-O-DMT-2’-Deoxy-N2-iBu-Guanosine

N2-iBu -5'-O-DMT -2'-dG

5'-O-DMTr-2'-dG(iBu)

5'-O-DMT-N2-ibu-2'-deoxyguanosine

5’-O-DMTr-2’-deoxyguanosine (N-ibu)

5'-O-[bis(4-methoxyphenyl)benzyl]-2'-deoxy-N-(2-methyl-1-oxopropyl)guanosine

68892-41-1

C35H37N5O7

Heterocyclic Building Blocks

Oligonucleotide Synthesis

Nucleoside Analogs