ChemicalBook > CAS DataBase List > DL-2,6-DIFLUOROPHENYLALANINE

DL-2,6-DIFLUOROPHENYLALANINE

Product Name
DL-2,6-DIFLUOROPHENYLALANINE
CAS No.
33787-05-2
Chemical Name
DL-2,6-DIFLUOROPHENYLALANINE
Synonyms
H-Phe(2,6-F2)-OH;TIMTEC-BB SBB000398;H-DL-Phe(2,6-F2)-OH;2,6-DIFLUOROPHENYLALANINE;H-2,6-DIFLUORO-PHE-OH HCL;DL-2,6-DIFLUOROPHENYLALANINE;L-2,6-DIFLUOROPHENYL-ALANINE;2,6-DIFLUORO-L-PHENYLALANINE;2,6-DIFLUORO-DL-PHENYLALANINE;L-Phenylalanine, 2,6-difluoro-
CBNumber
CB6197885
Molecular Formula
C9H9F2NO2
Formula Weight
201.17
MOL File
33787-05-2.mol
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DL-2,6-DIFLUOROPHENYLALANINE Property

Melting point:
256 °C
Boiling point:
301.1±42.0 °C(Predicted)
Density 
1.379±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
2.20±0.10(Predicted)
Appearance
off-white solid
CAS DataBase Reference
33787-05-2(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D451210
Product name
L-2,6-Difluorophenylalanine
Packaging
250mg
Price
$50
Updated
2021/12/16
Usbiological
Product number
231009
Product name
2,6-Difluoro-l-phenylalanine
Packaging
1g
Price
$252
Updated
2021/12/16
Matrix Scientific
Product number
089460
Product name
2,6-Difluoro-L-phenylalanine
Packaging
500mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD53598
Product name
2,6-Difluoro-l-phenylalanine
Packaging
500mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
089460
Product name
2,6-Difluoro-L-phenylalanine
Packaging
1g
Price
$76
Updated
2021/12/16
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DL-2,6-DIFLUOROPHENYLALANINE Chemical Properties,Usage,Production

Uses

L-2,6-Difluorophenylalanine

Synthesis

627910-22-9

33787-05-2

Step 4: (S)-2-phenoxymethylamino-3-(2,6-difluorophenyl)propanoic acid (2.2 g, 11 mmol) was dissolved in ethanol (25 mL) and 5% activated carbon loaded palladium catalyst (600 mg) was added. The hydrogenation reaction was carried out at 50 psi hydrogen pressure for 24 hours. Upon completion of the reaction, the catalyst was removed by Celite filtration and the solvent was evaporated under reduced pressure to give the crude product. The crude product was recrystallized from ether to give (S)-2-amino-3-(2,6-difluorophenyl)propionic acid (2.2 g, 80% yield). The product was identified by NMR hydrogen spectrum (DMSO-d6): δ 7.28 (m, 1H), 7.0 (t, J=7.6Hz, 2H), 2.77 (m, 2H). Mass spectrometry analysis showed: 202.2 (M+1), 199.7 (M-1).

References

[1] Patent: WO2005/28429, 2005, A2. Location in patent: Page/Page column 56
[2] Patent: WO2003/97617, 2003, A1. Location in patent: Page/Page column 43-44
[3] Patent: WO2004/108661, 2004, A1. Location in patent: Page/Page column 40
[4] Patent: WO2005/28454, 2005, A1. Location in patent: Page/Page column 43-44
[5] Patent: WO2006/34004, 2006, A2. Location in patent: Page/Page column 57

DL-2,6-DIFLUOROPHENYLALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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DL-2,6-DIFLUOROPHENYLALANINE Suppliers

China 53 Europe 2 France 1 Germany 2 India 1 Japan 1 United Kingdom 8 United States 16 Global 84
Alchem Pharmtech,Inc.
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View Lastest Price from DL-2,6-DIFLUOROPHENYLALANINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
DL-2,6-DIFLUOROPHENYLALANINE 33787-05-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-15
Career Henan Chemical Co
Product
DL-2,6-DIFLUOROPHENYLALANINE 33787-05-2
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2020-02-21

33787-05-2, DL-2,6-DIFLUOROPHENYLALANINERelated Search:

FMOC-D-PENTAFLUOROPHENYLALANINE DL-2,5-DIFLUOROPHENYLALANINE DL-3,4-DIFLUOROPHENYLALANINE DL-3,5-DIFLUOROPHENYLALANINE BOC-D-PENTAFLUOROPHENYLALANINE 2,3,6-Trifluoro-L-phenylalanine METHYL (2S)-2-AMINO-3-(2,3,6-TRIFLUOROPHENYL)PROPANOATE METHYL (2S)-2-AMINO-3-(2,6-DIFLUORO-3-METHYLPHENYL)PROPANOATE METHYL (2S)-2-AMINO-3-(3-CHLORO-2,6-DIFLUOROPHENYL)PROPANOATE 2,6-DIFLUORO-3-METHYL-DL-PHENYLALANINE BOC-L-PENTAFLUOROPHENYLALANINE 2,3,6-TRIFLUORO-DL-PHENYLALANINE 2,4,6-TRIFLUORO-DL-PHENYLALANINE 3-CHLORO-2,6-DIFLUORO-DL-PHENYLALANINE FMOC-L-PENTAFLUOROPHENYLALANINE METHYL (2S)-2-AMINO-3-(2,4,6-TRIFLUOROPHENYL)PROPANOATE DL-2,6-DIFLUOROPHENYLALANINE D-PENTAFLUOROPHE

  • 2,6-DIFLUOROPHENYLALANINE
  • 2,6-DIFLUORO-DL-PHENYLALANINE
  • 2,6-DIFLUORO-L-PHENYLALANINE
  • 2-AMINO-3-(2,6-DIFLUORO-PHENYL)-PROPIONIC ACID
  • L-2,6-DIFLUOROPHENYL-ALANINE
  • DL-2,6-DIFLUOROPHENYLALANINE
  • H-2,6-DIFLUORO-PHE-OH HCL
  • (S)-2-AMINO-3-(2,6-DIFLUORO-PHENYL)-PROPIONIC ACID
  • TIMTEC-BB SBB000398
  • (S)-2-amino-3-(2,6-difluorophenyl)propanoic acid
  • H-DL-Phe(2,6-F2)-OH
  • H-Phe(2,6-F2)-OH
  • L-Phenylalanine, 2,6-difluoro-
  • (2S)-2-amino-3-(2,6-difluorophenyl)propanoic acid
  • 33787-05-2
  • C9H9F2NO2HCl
  • Amino Acid Derivatives