ChemicalBook > CAS DataBase List > 4-ISOPROPYLPHENOXYACETIC ACID

4-ISOPROPYLPHENOXYACETIC ACID

Product Name: 4-ISOPROPYLPHENOXYACETIC ACID
CAS No.: 1643-16-9
Chemical Name: 4-ISOPROPYLPHENOXYACETIC ACID
Synonyms: AKOS BBB/199;LABOTEST-BB LT00454270;4-ISOPROPYLPHENOXYACETIC ACID;[(4-Isopropylphenyl)oxy]acetic acid;4-ISOPROPYLPHENOXYACETIC ACID, 98+%;2-(4-propan-2-ylphenoxy)ethanoic acid;2-[4-(1-Methylethyl)phenoxy]acetic acid;[[4-(1-Methylethyl)phenyl]oxy]acetic acid;Acetic acid, 2-[4-(1-methylethyl)phenoxy]-
CBNumber: CB6206633
Molecular Formula: C11H14O3
Formula Weight: 194.23
MOL File: 1643-16-9.mol

Less

4-ISOPROPYLPHENOXYACETIC ACID Property

Melting point:: 85-87°C
Boiling point:: 72-75℃ (3 Torr)
Density: 0.9450 g/cm3
refractive index: 1.4980 (589.3 nm 20℃)
storage temp.: Sealed in dry,Room Temperature
pka: 3.21±0.10(Predicted)
Appearance: Off-white to light yellow Solid
BRN: 2261017
InChI: InChI=1S/C11H14O3/c1-8(2)9-3-5-10(6-4-9)14-7-11(12)13/h3-6,8H,7H2,1-2H3,(H,12,13)
InChIKey: FPVCSFOUVDLTDG-UHFFFAOYSA-N
SMILES: C(O)(=O)COC1=CC=C(C(C)C)C=C1
CAS DataBase Reference: 1643-16-9(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36
HazardClass: IRRITANT
HS Code: 2918999090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TRC

Product number: I873915
Product name: 2-(4-Isopropylphenoxy)aceticAcid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 024034
Product name: 2-(4-Isopropylphenoxy)acetic acid
Packaging: 500mg
Price: $12
Updated: 2021/12/16

Apolloscientific

Product number: OR903364
Product name: 4-Isopropylphenoxyaceticacid
Purity: 95%
Packaging: 5g
Price: $145
Updated: 2021/12/16

Apolloscientific

Product number: OR903364
Product name: 4-Isopropylphenoxyaceticacid
Purity: 95%
Packaging: 25g
Price: $435
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0025937
Product name: 4-ISOPROPYLPHENOXYACETIC ACID
Purity: 95.00%
Packaging: 0.5G
Price: $638
Updated: 2021/12/16

Less

4-ISOPROPYLPHENOXYACETIC ACID Chemical Properties,Usage,Production

Synthesis

14062-21-6

1643-16-9

1. 4-Isopropylphenol (1.007 g, 7.39 mmol) was dissolved in 15 mL of dimethylformamide as starting material, potassium carbonate (2.04 g, 14.79 mmol) and ethyl bromoacetate (1.23 mL, 11.09 mmol) were added. The reaction mixture was stirred at room temperature for 48 hours. After completion of the reaction, the mixture was diluted with 500 mL of water and extracted with ether (2 x 200 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting crude product was purified by fast column chromatography (eluent: 10% ethyl acetate/hexane) to give 1.61 g (98%) of ethyl 4-isopropylphenoxyacetate as a colorless oil.MS (APCI) m/z: 223.3 [M + H]+. 1H NMR (400 MHz, CDCl3) δ: 7.14 (d, 2H), 6.84 (d, 2H) , 4.59 (s, 2H), 4.27 (q, 2H), 2.86 (m, 1H), 1.30 (t, 3H), 1.21 (d, 6H). 2. A mixture of ethyl 4-isopropylphenoxyacetate (1.61 g, 7.24 mmol) and 2 N NaOH aqueous solution (10.9 mL) in 20 mL of methanol was stirred at room temperature for 3 hr and then concentrated under reduced pressure. The residue was dissolved in 100 mL of water, acidified with 1 N aqueous hydrochloric acid to pH < 7, and then extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 1.32 g (94%) of 4-isopropylphenoxyacetic acid as a white solid.MS (APCI) m/z: 195.3 [M + H]+.1H NMR (400 MHz, CDCl3) δ: 7.17 (d, 2H), 6.86 (d, 2H), 4.66 (s, 2H) , 2.87 (m, 1H), 1.22 (d, 6H). 3. Benzyl 2-methyl-2-(3-piperidin-3-yl-phenoxy)-propionate (30 mg, 0.085 mmol) was dissolved in 1 mL of dichloromethane, 4-isopropylphenoxyacetic acid (33 mg, 0.17 mmol) and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (33 mg, 0.17 mmol) were added and stirred at room temperature for 18 hours. The reaction mixture was concentrated under reduced pressure and the crude product was purified by fast column chromatography (eluent: 30% ethyl acetate/hexane) to afford 35 mg (78%) of benzyl 2-(3-{1-{(4-isopropylphenoxy)acetyl]piperidin-3-yl}-phenoxy)-2-methyl-propanoate as a colorless oil.LC-MS m/z: 530.6 [M + H]+. 1H NMR (400 MHz, CDCl3) δ: 7.24 (m, 5H), 7.14 (m, 3H), 6.89 (m, 2H), 6.83 (m, 1H), 6.71 (s, 1H), 6.61 (d, 1H), 5.19 (s, 2H), 4.64 (m, 3H), 4.07 (d, 1H), 3.04 (t, 1H), 2.97 (m, 1H), 2.89 (m, 1H), 2.47 (m, 2H), 1.95 (m, 1H), 1.82 (m, 1H), 1.61 (s, 6H), 1.21 (d, 6H). 4. Benzyl 2-(3-{1-[(4-isopropylphenoxy)acetyl]piperidin-3-yl}-phenoxy)-2-methyl-propanoate (35 mg, 0.066 mmol) was dissolved in 2 mL of methanol, 10% palladium-carbon (4 mg, 10 wt%) was added, and hydrogenated at atmospheric pressure for 3 hours. The reaction mixture was filtered through diatomaceous earth and washed well with ethyl acetate. The filtrates were combined and concentrated under reduced pressure to give 29 mg (99%) of 2-(3-{1-[(4-isopropylphenoxy)acetyl]piperidin-3-yl}-phenoxy)-2-methyl-propanoic acid as a colorless oil.LC-MS m/z: 440.5 [M + H]+. 1H NMR (400 MHz, CDCl3) δ: 7.19 (t, 1H), 7.14 (t, 2H), 6.87 (m, 3H), 6.81 (m, 2H), 4.66 (m, 3H), 4.04 (dd, 1H), 3.05 (m, 1H), 2.85 (m, 1H), 2.65 (m, 2H), 2.02 (t, 1H), 1.82 (t, 1H), 1.65 (m, 1H), 1.59 (s, 6H), 1.21 (d, 6H). 1.21 (d, 6H).

References

[1] Patent: WO2004/48334, 2004, A1. Location in patent: Page 128-130

4-ISOPROPYLPHENOXYACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-ISOPROPYLPHENOXYACETIC ACID Suppliers

China 63 Germany 4 India 5 Russia 1 United Kingdom 5 United States 13 Global 91

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Zhengzhou GranLen pharmaceutical Technology Co., Ltd.

Tel: 0371-85513397
Email: info@granlen.com
Country: China
ProdList: 497
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Changzhou Boren Chemical Technology Co., Ltd.

Tel: 0519-82085178 13861172460
Fax: 0519-85859553
Email: sales@borenchem.cn
Country: China
ProdList: 96
Advantage: 60

Zhengzhou kangnuochenrui Chemical Technology Co.,Ltd

Tel: 18210788515
Fax: 18210788515
Email: zhuzixin999@163.c0m
Country: China
ProdList: 2999
Advantage: 55

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886750 13927877953
Fax: 0751-2886750
Email: 3005811397@qq.com
Country: China
ProdList: 13305
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Shanghai QiQiao Biological Technology Co., Ltd.

Tel: 021-37653318; 15221675714
Email: 515366396@qq.com
Country: China
ProdList: 2089
Advantage: 58

Nanjing NingFan Pharm-Tech CO. LTD.

Tel: 17368696818
Country: China
ProdList: 1984
Advantage: 58

Fuyang Ziyi Biological Pharmaceutical Co., Ltd.

Tel: 19308655899; 19308655899
Fax: -
Email: 2677609105@qq.com
Country: China
ProdList: 500
Advantage: 58

Jinan Liheng Biotechnology Co., Ltd.

Tel: 0531-18763987518 18763987518
Email: levi@lihengpharm.com
Country: China
ProdList: 1797
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Zhengzhou Granlen Sciences, ltd.

Tel: 0371-85513397 +86-18610099868
Email: info@granlen.com
Country: China
ProdList: 1890
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Changzhou Fullone Chemical Co., Ltd.

Tel: +86-13328197671 +86-13861172460
Email: sales@borenchem.cn
Country: China
ProdList: 1055
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Yuzhou Enthalpy Carbon Pharmaceutical Technology Co. LTD

Tel: 19963477321; 19963477321
Fax: QQ:2041275825
Email: 2041275825@qq.com
Country: China
ProdList: 1447
Advantage: 58

Guangzhou Yunmen Biotechnology Co., Ltd

Tel: 0751-18902340975/189023400307 18902340307
Fax: 0751-2819901
Email: 3356812514@qq.com
Country: China
ProdList: 9249
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Shandong Mingde Biotechnology Co., Ltd

Tel: 15553348166
Email: m15553348166@163.com
Country: China
ProdList: 9967
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai klamar Reagent Co., LTD

Tel: 4001650900 13817534909
Email: 3003940895@qq.com
Country: China
ProdList: 10714
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29784
Advantage: 58

Guangdong Fangxin Biotechnology Co., Ltd.

Tel: 0751-2838688 13376594225
Email: 1276075424@qq.com
Country: China
ProdList: 9942
Advantage: 58

Heze Bona Medical Technology Co., LTD

Tel: 18615487702
Email: 614989876@qq.com
Country: China
ProdList: 3000
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Changzhou Qianai Biotechnology Co., Ltd

Tel: 051915240519135 13961152745
Email: yudiguimo@126.COM
Country: China
ProdList: 10000
Advantage: 58

Auonsi (Shanghai) Biology Technology Co., Ltd.

Tel: 400-1107768 15058188853
Fax: 0571-88150696
Email: 478133536@qq.com
Country: China
ProdList: 8552
Advantage: 58

Shandong Mingde Biotechnology Co., Ltd.

Tel: 18560864701
Email: 643971@qq.com
Country: China
ProdList: 6098
Advantage: 58

Tianjin Rongshen Chemical Co., Ltd

Tel: 18317763565; 18317763565
Email: 18317763565@163.com
Country: China
ProdList: 9516
Advantage: 58

Less

View Lastest Price from 4-ISOPROPYLPHENOXYACETIC ACID manufacturers

Career Henan Chemical Co

Product: 4-isopropylphenoxyacetic acid 1643-16-9
Price: US $1.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 200kgs
Release date: 2020-01-09

1643-16-9, 4-ISOPROPYLPHENOXYACETIC ACIDRelated Search:

2-(2,4-Di-tert-pentylphenoxy)butryic acid O(1),O(3)-BIS(CARBOXYMETHYL)-O(2),O(4)-DIMETHYL-P-T-BUTYLCALIX(4)ARENE 4-ISOPROPYLPHENOXYACETIC ACID 4-TERT-BUTYLCALIX[4]ARENE-TETRAACETIC ACID TETRAETHYL ESTER 6,8-DI(TERT-BUTYL)-4-OXO-4H-CHROMENE-2-CARBOXYLIC ACID 2,4-Di(tert-amyl)phenoxyacetic acid 4-TERT-BUTYLPHENOXYACETIC ACID O(1),O(3)-BIS(ETHOXYCARBONYLMETHYL)-O(2),O(4)-DIMETHYL-P-TERT-BUTYLCALIX[4]ARENE O(1),O(3)-BIS(CARBETHOXYMETHYL)-P-TERT-BUTYLCALIX(4)ARENE Ciprofibrate Phenoxyacetic acid Cumene 1,3,5[10]-ESTRATRIENE-3,16ALPHA,17BETA-TRIOL 3-CARBOXYMETHYL ETHER 4,4'-ISOPROPYLIDENEDIPHENOXYACETIC ACID [4-(1-METHYL-1-PHENYLETHYL)PHENOXY]ACETIC ACID A-(P-TERT-BUTYLPHENOXY)PROPIONIC ACID CM-DCF-NAG B-ESTRADIOL 3-CARBOXYMETHYL ETHER

LABOTEST-BB LT00454270

2-(4-propan-2-ylphenoxy)ethanoic acid

4-ISOPROPYLPHENOXYACETIC ACID

AKOS BBB/199

4-ISOPROPYLPHENOXYACETIC ACID, 98+%

[(4-Isopropylphenyl)oxy]acetic acid

[[4-(1-Methylethyl)phenyl]oxy]acetic acid

Acetic acid, 2-[4-(1-methylethyl)phenoxy]-

2-[4-(1-Methylethyl)phenoxy]acetic acid

1643-16-9