ChemicalBook > CAS DataBase List > 2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
- Product Name
- 2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
- CAS No.
- 186826-17-5
- Chemical Name
- 2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
- Synonyms
- ML 10302;ML 10302 hydrochlorid;Monohydrochloride (9CI);2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE;2-(Piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate;2-(Piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride
- CBNumber
- CB6207933
- Molecular Formula
- C15H22Cl2N2O3
- Formula Weight
- 349.25
- MOL File
- Mol file
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2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Property
- storage temp.
- 2-8°C
- solubility
- DMSO: ~44 mg/mL
- form
- solid
- color
- white
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
TRC
- Product number
- M425050
- Product name
- ML10302Hydrochloride
- Packaging
- 100mg
- Price
- $155
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7413
- Product name
- ML10302hydrochloride
- Packaging
- 50mg
- Price
- $497
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7413
- Product name
- ML10302hydrochloride
- Packaging
- 10mg
- Price
- $119
- Updated
- 2021/12/16
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2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Chemical Properties,Usage,Production
Uses
Potent, selective 5-HT4 serotonin receptor agonist. New ester of 4-Amino-5-chloro-2-methoxybenzoic acid as potent agonist and antagonist for 5-HT4 receptors.
in vivo
ML 10302 hydrochloride (20?mg/kg; s.c.) induces the soluble form of amyloid precursor protein (sAPPα) production in the cortex of mice[3].
| Animal Model: | 8-weeks old adult male C57BL/6j wild-type mice (23-27?g)[3] |
| Dosage: | 5 mg/kg, 10 mg/kg, 20?mg/kg |
| Administration: | Subcutaneous injection |
| Result: | Significantly increased sAPPα level in the cortex. |
IC 50
5-HT4 Receptor: 4 nM (EC50); 5-HT4 Receptor: 1.07 nM (Ki); 5-HT3 Receptor: 782 nM (Ki)
2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
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2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Suppliers
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