ChemicalBook > CAS DataBase List > 2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE

2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE

Product Name
2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
CAS No.
186826-17-5
Chemical Name
2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
Synonyms
ML 10302;ML 10302 hydrochlorid;Monohydrochloride (9CI);2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE;2-(Piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate;2-(Piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride
CBNumber
CB6207933
Molecular Formula
C15H22Cl2N2O3
Formula Weight
349.25
MOL File
Mol file
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2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Property

storage temp. 
2-8°C
solubility 
DMSO: ~44 mg/mL
form 
solid
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M425050
Product name
ML10302Hydrochloride
Packaging
100mg
Price
$155
Updated
2021/12/16
ApexBio Technology
Product number
B7413
Product name
ML10302hydrochloride
Packaging
50mg
Price
$497
Updated
2021/12/16
ApexBio Technology
Product number
B7413
Product name
ML10302hydrochloride
Packaging
10mg
Price
$119
Updated
2021/12/16
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2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Chemical Properties,Usage,Production

Uses

Potent, selective 5-HT4 serotonin receptor agonist. New ester of 4-Amino-5-chloro-2-methoxybenzoic acid as potent agonist and antagonist for 5-HT4 receptors.

in vivo

ML 10302 hydrochloride (20?mg/kg; s.c.) induces the soluble form of amyloid precursor protein (sAPPα) production in the cortex of mice[3].

Animal Model:8-weeks old adult male C57BL/6j wild-type mice (23-27?g)[3]
Dosage:5 mg/kg, 10 mg/kg, 20?mg/kg
Administration:Subcutaneous injection
Result:Significantly increased sAPPα level in the cortex.

IC 50

5-HT4 Receptor: 4 nM (EC50); 5-HT4 Receptor: 1.07 nM (Ki); 5-HT3 Receptor: 782 nM (Ki)

2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE Suppliers

Canada 1 China 28 Switzerland 1 United Kingdom 2 United States 8 USA 1 Global 41
Tocris Bioscience
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Fax
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Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
CARBONE SCIENTIFIC CO.,LTD
Tel
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Fax
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Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
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186826-17-5, 2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATERelated Search:


  • ML 10302
  • 2-PIPERIDINOETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
  • Monohydrochloride (9CI)
  • 2-(Piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate
  • ML 10302 hydrochlorid
  • 2-(Piperidin-1-yl)ethyl 4-amino-5-chloro-2-methoxybenzoate hydrochloride
  • 186826-17-5
  • C15H21ClN2O3
  • C15H22Cl2N2O3
  • C15H21ClN2O3HCl
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals