ChemicalBook > CAS DataBase List > [H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2

[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2

Product Name
[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2
CAS No.
940291-10-1
Chemical Name
[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2
Synonyms
IDR-1;KSRIVPAIPVSLL;Anti-Infective Peptides;Innate Defense-Regulator Peptide;Innate defense regulator peptide-1;IDR-1, Innate Defense-Regulator Peptide;H-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-NH2;(2S)-1-formyl-N-[(2S)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide,propane;[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2;L-Leucinamide, L-lysyl-L-seryl-L-arginyl-L-isoleucyl-L-valyl-L-prolyl-L-alanyl-L-isoleucyl-L-prolyl-L-valyl-L-seryl-L-leucyl-
CBNumber
CB62097684
Molecular Formula
C65H118N18O15
Formula Weight
1391.74
MOL File
940291-10-1.mol
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[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2 Property

storage temp. 
−20°C
form 
Solid
color 
White to off-white
Sequence
H-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-NH2
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Hazard and Precautionary Statements (GHS)

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[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2 Chemical Properties,Usage,Production

Uses

IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release[1][2].

References

[1] Monisha G Scott, et al. An Anti-Infective Peptide That Selectively Modulates the Innate Immune Response. Nat Biotechnol. 2007 Apr;25(4):465-72. DOI:10.1038/nbt1288
[2] Man Hou, et al. Antimicrobial Peptide LL-37 and IDR-1 Ameliorate MRSA Pneumonia in Vivo. Cell Physiol Biochem. 2013;32(3):614-23. DOI:10.1159/000354465

[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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[H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2 Suppliers

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940291-10-1, [H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2Related Search:


  • [H]-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-[NH2], Innate defense regulator peptide-1, KSRIVPAIPVSLL-NH2
  • IDR-1
  • H-Lys-Ser-Arg-Ile-Val-Pro-Ala-Ile-Pro-Val-Ser-Leu-Leu-NH2
  • Innate Defense-Regulator Peptide
  • Innate defense regulator peptide-1
  • KSRIVPAIPVSLL
  • IDR-1, Innate Defense-Regulator Peptide
  • Anti-Infective Peptides
  • L-Leucinamide, L-lysyl-L-seryl-L-arginyl-L-isoleucyl-L-valyl-L-prolyl-L-alanyl-L-isoleucyl-L-prolyl-L-valyl-L-seryl-L-leucyl-
  • (2S)-1-formyl-N-[(2S)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide,propane
  • 940291-10-1
  • C65H118N18O15