(R)-(+)-SKF-38393 hydrochloride
- Product Name
- (R)-(+)-SKF-38393 hydrochloride
- CAS No.
- 81702-42-3
- Chemical Name
- (R)-(+)-SKF-38393 hydrochloride
- Synonyms
- R-SKF-38393A HCl;R(+)-SKF-38393 HYDROCHLORIDE;RSKF38393A HCl,R SKF 38393A HCl
- CBNumber
- CB62129530
- Molecular Formula
- C16H17NO2.ClH
- Formula Weight
- 291.776
- MOL File
- 81702-42-3.mol
(R)-(+)-SKF-38393 hydrochloride Property
- Melting point:
- 244-246 °C
- solubility
- 0.1 M HCl: soluble1.2mg/mL
- form
- solid
- color
- off-white to light tan
- optical activity
- [α]22/D +16.1°, c = 1.2 in methanol(lit.)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S101
- Product name
- (R)-(+)-SKF-38393 hydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $268
- Updated
- 2024/03/01
- Product number
- 5.05881
- Product name
- (R)-(+)-SKF38393 Hydrochloride - CAS 81702-42-3 - Calbiochem
- Packaging
- 5mg
- Price
- $225
- Updated
- 2024/03/01
- Product number
- S101
- Product name
- (R)-(+)-SKF-38393 hydrochloride
- Purity
- ≥98% (HPLC), solid
- Packaging
- 100mg
- Price
- $2380
- Updated
- 2023/01/07
- Product number
- S550085
- Product name
- (R)-(+)-SKF-38393 hydrochloride
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- INB0004651
- Product name
- (R)-(+)-SKF-38393 HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $775.01
- Updated
- 2021/12/16
(R)-(+)-SKF-38393 hydrochloride Chemical Properties,Usage,Production
Uses
(R)-(+)-SKF-38393 Hydrochloride is the active enantiomer of (±)-SKF-38393, a D1 dopamine receptor agonist.
Uses
(R)-(+)-SKF-38393 hydrochloride has been used as a D1 dopamine receptor agonist to study its effect on the sleep-wake pattern of macaques rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Biochem/physiol Actions
(R)-(+)-SKF-38393 hydrochloride is a D1 dopamine receptor agonist and an active enantiomer of (±)-SKF-38393. It enhances pertussis toxin-insensitive and protein kinase A-mediated glutamate release in the hippocampal neurons. SKF-38393, a?benzazepine derivative, exhibits anorectic effects.
(R)-(+)-SKF-38393 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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