ChemicalBook > CAS DataBase List > (R)-(+)-SKF-38393 hydrochloride

(R)-(+)-SKF-38393 hydrochloride

Product Name
(R)-(+)-SKF-38393 hydrochloride
CAS No.
81702-42-3
Chemical Name
(R)-(+)-SKF-38393 hydrochloride
Synonyms
R-SKF-38393A HCl;R(+)-SKF-38393 HYDROCHLORIDE;RSKF38393A HCl,R SKF 38393A HCl;(R)-(+)-SKF-38393 hydrochloride;(R)-(+)-SKF38393 hydrochloride, D1 partial agonist
CBNumber
CB62129530
Molecular Formula
C16H17NO2.ClH
Formula Weight
291.776
MOL File
81702-42-3.mol
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(R)-(+)-SKF-38393 hydrochloride Property

Melting point:
244-246 °C
storage temp. 
-20°C
solubility 
0.1 M HCl: soluble1.2mg/mL
form 
solid
color 
off-white to light tan
optical activity
[α]22/D +16.1°, c = 1.2 in methanol(lit.)
Water Solubility 
water: 100mM
InChI
1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H/t14-;/m1./s1
InChIKey
YEWHJCLOUYPAOH-PFEQFJNWSA-N
SMILES
Cl.Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-22
WGK Germany 
3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S101
Product name
(R)-(+)-SKF-38393 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$296
Updated
2026/03/19
Sigma-Aldrich
Product number
5.05881
Product name
(R)-(+)-SKF38393 Hydrochloride - CAS 81702-42-3 - Calbiochem
Packaging
5mg
Price
$247
Updated
2026/03/19
Sigma-Aldrich
Product number
S101
Product name
(R)-(+)-SKF-38393 hydrochloride
Purity
≥98% (HPLC), solid
Packaging
100mg
Price
$2380
Updated
2023/01/07
TRC
Product number
S550085
Product name
(R)-(+)-SKF-38393 hydrochloride
Packaging
5mg
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0004651
Product name
(R)-(+)-SKF-38393 HYDROCHLORIDE
Purity
95.00%
Packaging
5MG
Price
$775.01
Updated
2021/12/16
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(R)-(+)-SKF-38393 hydrochloride Chemical Properties,Usage,Production

Uses

(R)-(+)-SKF-38393 Hydrochloride is the active enantiomer of (±)-SKF-38393, a D1 dopamine receptor agonist.

Uses

(R)-(+)-SKF-38393 hydrochloride has been used as a D1 dopamine receptor agonist to study its effect on the sleep-wake pattern of macaques rendered parkinsonian with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

Biochem/physiol Actions

(R)-(+)-SKF-38393 hydrochloride is a D1 dopamine receptor agonist and an active enantiomer of (±)-SKF-38393. It enhances pertussis toxin-insensitive and protein kinase A-mediated glutamate release in the hippocampal neurons. SKF-38393, abenzazepine derivative, exhibits anorectic effects.

(R)-(+)-SKF-38393 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-SKF-38393 hydrochloride Suppliers

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81702-42-3, (R)-(+)-SKF-38393 hydrochlorideRelated Search:


  • R(+)-SKF-38393 HYDROCHLORIDE
  • R-SKF-38393A HCl
  • RSKF38393A HCl,R SKF 38393A HCl
  • (R)-(+)-SKF38393 hydrochloride, D1 partial agonist
  • (<i>R</i>)-(+)-SKF-38393 hydrochloride
  • 81702-42-3