Palonosetron

ChemicalBook > CAS DataBase List > Palonosetron

Product Name: Palonosetron
CAS No.: 149653-99-6
Chemical Name: Palonosetron
Synonyms: CID 148211;Palonosetron USP/EP/BP;(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one;[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one;1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-
CBNumber: CB62131052
Molecular Formula: C19H24N2O
Formula Weight: 296.41
MOL File: 149653-99-6.mol

Less

Palonosetron Property

Boiling point:: 470.4±45.0 °C(Predicted)
Density: 1.24
pka: 9.77±0.33(Predicted)

Less

Hazard and Precautionary Statements (GHS)

Less

Palonosetron Chemical Properties,Usage,Production

Indications

Palonosetron is approved by the US FDA for acute and delayed CINV and PONV.

Biological Activity

Palonosetron is a highly selective, high-affinity 5-HT3 receptor antagonist. Due to its structural difference from the first-generation 5-HT3 receptor antagonists, palonosetron has an affinity for the 5-HT3 receptor at least 30 times that of other similar drugs.

in vitro

Palonosetron is neither an inhibitor of CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2D6, CYP2E1 and CYP3A4/5 (CYP2C19 not studied) nor does it induce the activity of CYP1A2, CYP2D6 or CYP3A4/5.

Palonosetron Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Palonosetron Suppliers

China 37 India 1 United States 1 Global 39

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-010-52878169 15801002657
Email: sales@bjcomparison.com
Country: China
ProdList: 4820
Advantage: 58

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Hubei widely chemical technology Co., Ltd.

Tel: 027-83991130 18627774460
Fax: 027-83991130
Email: 1718093273@QQ.COM
Country: China
ProdList: 1879
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Hubei Changrun Biomedical Technology Co., Ltd.

Tel: 027-63496417 13007129042
Fax: 13476107660
Email: 3294393103@qq.com
Country: China
ProdList: 296
Advantage: 58

Changzhou Yongfeng Biomedicine Co. Ltd.

Tel: 15006117673
Fax: 2973592490@.com
Email: 2973592490@qq.com
Country: China
ProdList: 299
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 260366801@qq.com
Country: China
ProdList: 7824
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 22787
Advantage: 58

Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.

Tel: 020-89854820
Email: sales@jzpharma.cn
Country: China
ProdList: 1130
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49476
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29809
Advantage: 58

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Tel: 0755-0755-0755-83725350 13380397412
Fax: 0755-28094224
Email: 3001280422@qq.com
Country: China
ProdList: 10005
Advantage: 58

Hubei Yuanmeng Biotechnology Co., Ltd

Tel: 027-68897569 18120462897
Fax: 027-68897569
Email: fiona@yuanmengbio.com
Country: China
ProdList: 3532
Advantage: 58

Jiangxi ravel Biotechnology Co.,Ltd

Tel: 18502762009
Email: 721846333@qq.com
Country: China
ProdList: 2449
Advantage: 58

Shenzhen Roark Pharma-Tec Co., Ltd.

Tel: 13128912434
Email: 2880126944@qq.com
Country: China
ProdList: 2577
Advantage: 58

Nanjing Wogni Chemical Co., Ltd.

Tel: 15996452985
Email: foxerhy@163.com
Country: China
ProdList: 4939
Advantage: 58

Aikon International Limited

Tel: 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 10715
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 30016
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-81123119 15529505138
Email: 1021@dideu.com
Country: China
ProdList: 9983
Advantage: 58

Nantong Hanfang Biotechnology Co. , Ltd.

Tel: 18616537568
Email: hanfangpharma@126.com
Country: China
ProdList: 29981
Advantage: 58

SHANGHAI KEAN TECHNOLOGY CO., LTD.

Tel: +8613817748580
Fax: 021-50175322
Email: cooperation@kean-chem.com
Country: China
ProdList: 40066
Advantage: 58

Shanghai Acmec Biochemical Technology Co., Ltd.

Tel: +86-18621343501; +undefined18621343501
Email: product@acmec-e.com
Country: China
ProdList: 33338
Advantage: 58

Henan Allgreen Chemical Co.,LTD

Tel: +86-37155567971 +86-13633837469
Email: info@allgreenchem.com
Country: China
ProdList: 5996
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Beijing Wintic Pharma Co.,Ltd

Tel: --
Fax: --
Email: songtaoli@263.net
Country: China
ProdList: 78
Advantage: 34

Shanghai Triton Chemtech Co., Ltd

Tel: --
Fax: --
Email: info@tritonchemtech.com
Country: China
ProdList: 204
Advantage: 38

Hangzhou CNRU Pharm&Chem Co., Ltd

Tel: --
Fax: --
Email: sales@canruipharm.com
Country: China
ProdList: 67
Advantage: 50

Hangzhou Heta Pharm & Chem Co., Ltd

Tel: --
Fax: --
Email: sales@hetapharm.com
Country: China
ProdList: 133
Advantage: 54

Chengdu Entry Scientific and Technological Development Co., Ltd

Tel: --
Fax: --
Country: China
ProdList: 31
Advantage: 51

Beijing Tongqing Putian Science & Technology Development Co., Ltd

Tel: --
Fax: --
Email: sales@putianchem.com
Country: China
ProdList: 71
Advantage: 64

Kang-Sun Pharmaceutical Limited

Tel: --
Fax: --
Email: kangsunpharma@gmail.com
Country: China
ProdList: 48
Advantage: 50

Less

View Lastest Price from Palonosetron manufacturers

Dideu Industries Group Limited

Product: Palonosetron 149653-99-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-09

149653-99-6, PalonosetronRelated Search:

2,2,4-Trimethylpentane Dolasetron mesylate N-OCTANE Granisetron hydrochloride Granisetron Palonosetron Hydrochloride RS 42358-197 PALONOSETRON HCL 6-Hydroxy Palonosetron Palonosetron impurity (S,R)-Palonosetron Hydrochloride (R,S)-Palonosetron Hydrochloride Palonosetron Impurity 11 Palonosetron Impurity 7 Palonosetron Impurity 12 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- (6S)-Hydroxy (S,S)-Palonosetron 1H-Benz[de]isoquinolin-1-one,2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,(3aS)-

[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one

CID 148211

1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-

Palonosetron USP/EP/BP

(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one

149653-99-6