ChemicalBook > CAS DataBase List > Palonosetron
Palonosetron
- Product Name
- Palonosetron
- CAS No.
- 149653-99-6
- Chemical Name
- Palonosetron
- Synonyms
- CID 148211;Palonosetron USP/EP/BP;(R)-2-((R)-quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de] isoquinolin-1-one;[r-(r*,r*)]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one;1H-Benz[de]isoquinolin-1-one, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-
- CBNumber
- CB62131052
- Molecular Formula
- C19H24N2O
- Formula Weight
- 296.41
- MOL File
- 149653-99-6.mol
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Palonosetron Property
- Boiling point:
- 470.4±45.0 °C(Predicted)
- Density
- 1.24
- pka
- 9.77±0.33(Predicted)
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Palonosetron Chemical Properties,Usage,Production
Indications
Palonosetron is approved by the US FDA for acute and delayed CINV and PONV.
Biological Activity
Palonosetron is a highly selective, high-affinity 5-HT3 receptor antagonist. Due to its structural difference from the first-generation 5-HT3 receptor antagonists, palonosetron has an affinity for the 5-HT3 receptor at least 30 times that of other similar drugs.
in vitro
Palonosetron is neither an inhibitor of CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2D6, CYP2E1 and CYP3A4/5 (CYP2C19 not studied) nor does it induce the activity of CYP1A2, CYP2D6 or CYP3A4/5.
Palonosetron Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Palonosetron manufacturers
Dideu Industries Group Limited
- Product
- Palonosetron 149653-99-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-09
149653-99-6, PalonosetronRelated Search:
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Palonosetron Hydrochloride
RS 42358-197
PALONOSETRON HCL
6-Hydroxy Palonosetron
Palonosetron impurity
(S,R)-Palonosetron Hydrochloride
(R,S)-Palonosetron Hydrochloride
Palonosetron Impurity 11
Palonosetron Impurity 7
Palonosetron Impurity 12
1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-
(6S)-Hydroxy (S,S)-Palonosetron
1H-Benz[de]isoquinolin-1-one,2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-,(3aS)-