ESTRONE-2,4-D2 Property

Melting point:

259 - 261°C

storage temp. 

Refrigerator

solubility 

Chloroform (Slightly, Sonicated), Ethanol (Slightly, Sonicated) Methanol (Slightly)

form 

Solid

color 

White to Off-White

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H351Suspected of causing cancer

H360May damage fertility or the unborn child

H362May cause harm to breast-fed children

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

ESTRONE-2,4-D2 Chemical Properties,Usage,Production

Description

Estrone-d₂ is intended for use as an internal standard for the quantification of estrone (Item Nos. ISO60165 | 10006485) by GC- or LC-MS. Estrone is one of the three naturally occurring estrogens, the others being estradiol (Item Nos. ISO60155 | 10006315) and estriol (Item Nos. ISO60164 | 10006484). Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver. Serum concentrations of estrone in premenopausal women fluctuate according to the menstrual cycle and becomes the most predominant estrogen in postmenopausal women. The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.

Uses

Estrone-2,4-d2 (CAS# 350820-16-5) is a useful isotopically labeled research compound. It could potentially be useful as a wetland substrate for the removal of pharmaceutical and personal care products from contaminated water.