AMinoiMinoMethanesulfonic Acid Property

Melting point:

132-134℃ (decomposition)

Density 

2.09±0.1 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

solubility 

DMSO (Very Slightly), Methanol (Slightly, Heated)

pka

7.74±0.40(Predicted)

form 

Solid

color 

White to Off-White

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

AMinoiMinoMethanesulfonic Acid Chemical Properties,Usage,Production

Description

AMinoiMinoMethanesulfonic Acid is a parent compound and its derivatives guanylate amines; some derivatives give triazoles with azide and  aminoiminoethanenitriles with cyanide as nucleophile.

Chemical Properties

White Solid

Uses

AMinoiMinoMethanesulfonic Acid can be used to prepare Guanidine derivatives.

Preparation

Preparative Methods of AMinoiMinoMethanesulfonic Acid: by the oxidation of thiourea or aminoiminomethanesulfinic acid  (formamidinesulfinic acid) with Peracetic Acid. Many substituted aminoiminomethanesulfonic acids can  be prepared in the same way. Others have utilized Hydrogen Peroxide with sodium molybdate as a  catalyst to oxidize the corresponding thioureas to a variety of monosubstituted aminoiminomethanesulfonic acids; the substituents include phenyl, 2-methylphenyl, 4-fluorophenyl, n-propyl, cyclohexylmethyl, S-α- methylbenzyl, cyclooctyl, and benzhydryl.

storage

AMinoiMinoMethanesulfonic Acid is stable for at least a few weeks at room temperature. After drying, it  remains stable for at least 5 months if kept in a freezer. Thiourea and its metabolites (probably oxidized  thiourea) are tumorigenic and cause lung edema. All direct contact with the compound should be avoided;  for example, a dust mask should be worn. All residues should be destroyed with strong bleach solution.  Many substituted thioureas and their metabolites are also biologically active. Use in a fume hood.