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(2E)-3-(1H-Imidazole-4-yl)propenoic acid

Product Name
(2E)-3-(1H-Imidazole-4-yl)propenoic acid
CAS No.
3465-72-3
Chemical Name
(2E)-3-(1H-Imidazole-4-yl)propenoic acid
Synonyms
Chebi:30817;Trans-uric acid;(E)-Urocanic acid;trans-Urocanic acid;trans-UrocanicAcid>Thiamazole Impurity 5;trans-Urocanic Acid;(E)-3-(4-Imidazolyl)acrylic acid;(αE)-1H-Imidazole-4-acrylic acid;(E)-3-(5-Imidazolyl)acrylic Acid
CBNumber
CB62225096
Molecular Formula
C6H6N2O2
Formula Weight
138.12
MOL File
3465-72-3.mol
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(2E)-3-(1H-Imidazole-4-yl)propenoic acid Property

Melting point:
225 °C
Boiling point:
456.9±20.0 °C(Predicted)
Density 
1.430±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMF: 3 mg/ml; DMSO: 15 mg/ml; PBS (pH 7.2): 0.3 mg/ml
form 
powder to crystal
pka
3.55±0.10(Predicted)
color 
White to Almost white
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Safety

HS Code 
2933.29.9000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
I0002
Product name
trans-Urocanic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$135
Updated
2025/07/31
Cayman Chemical
Product number
16228
Product name
trans-Urocanic Acid
Purity
≥98%
Packaging
1g
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
16228
Product name
trans-Urocanic Acid
Purity
≥98%
Packaging
5g
Price
$134
Updated
2024/03/01
TRC
Product number
I577448
Product name
(E)-3-(1H-Imidazol-5-yl)acrylicAcid
Packaging
5g
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
176213
Product name
(E)-3-(1H-Imidazol-4-yl)-2-propenoic acid
Packaging
5g
Price
$810
Updated
2021/12/16
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(2E)-3-(1H-Imidazole-4-yl)propenoic acid Chemical Properties,Usage,Production

Uses

trans-urocanic acid (trans-UCA), a natural epidermal constituent, inhibits human natural killer cell (NK) activity in vitro. trans-urocanic acid is active in regulating an immune function[1].

Definition

ChEBI: The trans-isomer of urocanic acid.

IC 50

Human Endogenous Metabolite

References

[1] J Uksila, et al. Trans-urocanic acid, a natural epidermal constituent, inhibits human natural killer cell activity in vitro. Exp Dermatol. 1994 Apr;3(2):61-5. DOI:10.1111/j.1600-0625.1994.tb00048.x
[2] Kazuyo Kaneko, et al. cis-Urocanic acid enhances prostaglandin E2 release and apoptotic cell death via reactive oxygen species in human keratinocytes. J Invest Dermatol. 2011 Jun;131(6):1262-71. DOI:10.1038/jid.2011.37

(2E)-3-(1H-Imidazole-4-yl)propenoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(2E)-3-(1H-Imidazole-4-yl)propenoic acid Suppliers

Americas 1 China 57 Europe 1 India 2 Japan 1 United States 6 Global 68
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from (2E)-3-(1H-Imidazole-4-yl)propenoic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
(2E)-3-(1H-Imidazole-4-yl)propenoic acid 3465-72-3
Price
US $0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-08-01

3465-72-3, (2E)-3-(1H-Imidazole-4-yl)propenoic acidRelated Search:

TRAUMATIC ACID Inositol Urocanic acid 5-HYDROXYBARBITURIC ACID 7-METHYLURIC ACID

  • (2E)-3-(1H-Imidazole-4-yl)acrylic acid
  • (2E)-3-(1H-Imidazole-4-yl)propenoic acid
  • (E)-3-(1H-Imidazol-4-yl)propenoic acid
  • (E)-Urocanic acid
  • (αE)-1H-Imidazole-4-acrylic acid
  • trans-Urocanic acid
  • (2E)-3-(1H-Imidazol-4-yl)acrylic acid
  • (2E)-3-(1H-Imidazol-4-yl)prop-2-enoic acid
  • Chebi:30817
  • <i>trans</i>-Urocanic Acid
  • (E)-3-(4-Imidazolyl)acrylic acid
  • Trans-uric acid
  • trans-UrocanicAcid&gt
  • 2-Propenoic acid, 3-(1H-imidazol-5-yl)-, (2E)-
  • transUrocanic Acid,trans Urocanic Acid
  • Thiamazole Impurity 5
  • (E)-3-(5-Imidazolyl)acrylic Acid
  • (E)-3-(1H-imidazol-5-yl)prop-2-enoic acid
  • 3465-72-3