(-)-3-Demethylcolchicine

Product Name: (-)-3-Demethylcolchicine
CAS No.: 7336-33-6
Chemical Name: (-)-3-Demethylcolchicine
Synonyms: Desmethylcolchicine;3-Demethylcolchicine;O3-Demethylcolchicine;3-DesMethylcolchicine;3-O-Demethylcolchicine;(-)-3-Demethylcolchicine;Colchicine EP Impurity E;Colchicine 3-Demethyl Impurity;3-demethylcolchicine, 10 mM in DMSO;Colchicine Impurity 5（Colchicine EP Impurity E）
CBNumber: CB62228507
Molecular Formula: C21H23NO6
Formula Weight: 385.41
MOL File: 7336-33-6.mol

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(-)-3-Demethylcolchicine Property

Melting point:: 163-166°C
Boiling point:: 768.3±60.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: DMSO : 100 mg/mL (259.46 mM; Need ultrasonic)
form: A solid
pka: 9.53±0.40(Predicted)
color: White to yellow
InChI: InChI=1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-17(25)20(27-3)21(28-4)19(12)13-6-8-18(26-2)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1
InChIKey: JRRUSQGIRBEMRN-HNNXBMFYSA-N
SMILES: C(N[C@@H]1C2C(C3=C(OC)C(OC)=C(O)C=C3CC1)=CC=C(OC)C(=O)C=2)(=O)C

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Safety

Toxicity: LD50 intraperitoneal in mouse: 570ug/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H318Causes serious eye damage

H330Fatal if inhaled

H340May cause genetic defects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FD20991
Product name: (-)-3-Demethylcolchicine
Packaging: 2mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD20991
Product name: (-)-3-Demethylcolchicine
Packaging: 5mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD20991
Product name: (-)-3-Demethylcolchicine
Packaging: 10mg
Price: $125
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD20991
Product name: (-)-3-Demethylcolchicine
Packaging: 25mg
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD20991
Product name: (-)-3-Demethylcolchicine
Packaging: 50mg
Price: $340
Updated: 2021/12/16

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(-)-3-Demethylcolchicine Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

A metabolite of Colchicine (C640000). Has shown anti-tumor activity.

(-)-3-Demethylcolchicine Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)-3-Demethylcolchicine Suppliers

Canada 1 China 78 India 7 United Kingdom 1 United States 8 Global 95

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Tel: 0755-0755-83725350 13380397412
Fax: 0755-28094224
Email: 3001280422@qq.com
Country: China
ProdList: 10001
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5158
Advantage: 50

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
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Shanghai YuanYe Biotechnology Co., Ltd.

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Fax: QQ:3008007432
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Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-0755-28967200-8062 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9624
Advantage: 60

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View Lastest Price from (-)-3-Demethylcolchicine manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Colchicine EP Impurity E 7336-33-6
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-26

7336-33-6, (-)-3-DemethylcolchicineRelated Search:

Colchicine

(-)-3-Demethylcolchicine

(S)-7-Acetylamino-6,7-dihydro-3-hydroxy-1,2,10-trimethoxybenzo[a]heptalen-9(5H)-one

3-Demethylcolchicine

3-O-Demethylcolchicine

3-DesMethylcolchicine

N-[(7S)-5,6,7,9-Tetrahydro-3-hydroxy-1,2,10-triMethoxy-9-oxobenzo[a]heptalen-7-yl]-acetaMide

N-[[(7S)-3-Hydroxy-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalene]-7α-yl]acetamide

O3-Demethylcolchicine

Colchicine EP Impurity E

Colchicine Impurity 5（Colchicine EP Impurity E）

N-[(7S)-3-hydroxy-1,2,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide

Colchicine 3-Demethyl Impurity

Acetamide, N-[(7S)-5,6,7,9-tetrahydro-3-hydroxy-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-

(S)-N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

Colchicine EP Impurity E (3-O-Demethyl Colchicine)

Desmethylcolchicine

carrageenin,3 demethylcolchicine,inhibit,Inhibitor,scavenging,colchicine,3-Demethylcolchicine,edema,Reactive Oxygen Species,metabolite,3demethylcolchicine,radical

N-(3-hydroxy-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

N-[(7S,12aRa)-3-Hydroxy-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (3

3-demethylcolchicine, 10 mM in DMSO

N-[(7S,12aRa)-3-Hydroxy-1,2,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (3-O-Demethylcolchicine)

7336-33-6

73336-33-6

Chiral Reagents

Inhibitors

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals