Levofloxacin N-oxide
- Product Name
- Levofloxacin N-oxide
- CAS No.
- 117678-38-3
- Chemical Name
- Levofloxacin N-oxide
- Synonyms
- Levofloxacin-3;(S)-4-(6-carboxy-9;Levofloxacin N-oxide;Levofloxacin N-Oxide 1;Levofloacin Impurity 2;levofloxacin N-oxide832;1-Methyl-4-[(9-fluoro-2;Levofloxacin BP Impurity C;Levofloxacin nitrogen oxide;Levofloxacin Impurity C(EP)
- CBNumber
- CB62256870
- Molecular Formula
- C18H20FN3O5
- Formula Weight
- 377.3669032
- MOL File
- 117678-38-3.mol
Levofloxacin N-oxide Property
- Melting point:
- >146°C (dec.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 5.19±0.40(Predicted)
- color
- Off-White to Pale Green
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C18H20FN3O5/c1-10-9-27-17-14-11(16(23)12(18(24)25)8-21(10)14)7-13(19)15(17)20-3-5-22(2,26)6-4-20/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1
- InChIKey
- MVLAUMUQGRQERL-JTQLQIEISA-N
- SMILES
- O1C2=C(N3CC[N+]([O-])(C)CC3)C(F)=CC3C(=O)C(C(O)=O)=CN(C2=3)[C@@H](C)C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H361Suspected of damaging fertility or the unborn child
H362May cause harm to breast-fed children
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy/while nursing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 27177
- Product name
- Levofloxacin N-oxide
- Packaging
- 5mg
- Price
- $116
- Updated
- 2024/03/01
- Product number
- 27177
- Product name
- Levofloxacin N-oxide
- Packaging
- 25mg
- Price
- $343
- Updated
- 2024/03/01
- Product number
- 27177
- Product name
- Levofloxacin N-oxide
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 27177
- Product name
- Levofloxacin N-oxide
- Packaging
- 10mg
- Price
- $199
- Updated
- 2024/03/01
- Product number
- L360040
- Product name
- LevofloxacinN-oxide
- Packaging
- 25mg
- Price
- $180
- Updated
- 2021/12/16
Levofloxacin N-oxide Chemical Properties,Usage,Production
Description
Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin . Levofloxacin N-oxide is also a degradation product of levofloxacin that is formed through exposure to daylight or hydrogen peroxide.
Uses
Levofloxacin N-oxide is an impurity of Ofloxacin (O245750), which is a fluorinated quinolone antibacterial.
References
[1] A HEMERYCK. Pharmacokinetics, metabolism, excretion and plasma protein binding of 14C-levofloxacin after a single oral administration in the Rhesus monkey.[J]. Xenobiotica, 2006, 36 7: 597-613. DOI: 10.1080/00498250600674436
[2] Levofloxacin[J]. Reactions Weekly, 2018, 17 1: 232. DOI: 10.1007/s40278-018-53210-y
[3] ANDRZEJ CZYRSKI Artur T Katarzyna Anusiak. The degradation of levofloxacin in infusions exposed to daylight with an identification of a degradation product with HPLC-MS.[J]. Scientific Reports, 2019: 3621. DOI: 10.1038/s41598-019-40201-9
[4] M. LALITHA DEVI K. B C. A validated stability-indicating RP-HPLC method for levofloxacin in the presence of degradation products, its process related impurities and identification of oxidative degradant[J]. Journal of pharmaceutical and biomedical analysis, 2009, 50 5: Pages 710-717. DOI: 10.1016/j.jpba.2009.05.038
Levofloxacin N-oxide Preparation Products And Raw materials
Raw materials
Preparation Products
Levofloxacin N-oxide Suppliers
- Tel
- 13316949107 13316968096
- 1979313431@qq.com
- Country
- China
- ProdList
- 9564
- Advantage
- 58
- Tel
- 0755-0755-83725350 13380397412
- Fax
- 0755-28094224
- 3001280422@qq.com
- Country
- China
- ProdList
- 10001
- Advantage
- 58
- Tel
- 0755-4000505016 13380397412
- Fax
- 0755 28094224
- 3001272453@qq.com
- Country
- China
- ProdList
- 5158
- Advantage
- 50
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 18333
- Advantage
- 56
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- 027-87465837 19945049750
- Fax
- 027-8777-2287
- sales@finetechnology-ind.com
- Country
- China
- ProdList
- 9637
- Advantage
- 58
- Tel
- 0531-68652053 15863796298;
- 2310993908@qq.com
- Country
- China
- ProdList
- 2437
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 0755-83552066 15986688328
- Fax
- 0755-83552066
- service@roarkstandards.com
- Country
- China
- ProdList
- 1442
- Advantage
- 58