ChemicalBook > CAS DataBase List > 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
Uses- Product Name
- 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
- CAS No.
- 24922-00-7
- Chemical Name
- 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
- Synonyms
- Cyclopentanepropanoicacid, b-oxo;ETHYL 3-CYCLOPENTYL-3-OXOPROPANOATE;Ethyl 3-cyclopentyl-3-oxopropionate;Cyclopentanepropanoicacid, b-oxo-, ethyl ester;3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER;Cyclopentanepropanoic acid, β-oxo-, ethyl ester
- CBNumber
- CB6234007
- Molecular Formula
- C10H16O3
- Formula Weight
- 184.23
- MOL File
- 24922-00-7.mol
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3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER Property
- Boiling point:
- 91-94 °C(Press: 1.8 Torr)
- Density
- 1.065±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 10.51±0.20(Predicted)
- Appearance
- Colorless to light yellow Liquid
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Safety
- HS Code
- 2918999090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H227Combustible liquid
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
TRC
- Product number
- E926825
- Product name
- Ethyl3-Cyclopentyl-3-oxopropanoate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0129381
- Product name
- 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1443.17
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0129381
- Product name
- 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER
- Purity
- 95.00%
- Packaging
- 10G
- Price
- $2328.48
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 2229-1-76
- Product name
- Ethyl 3-cyclopentyl-3-oxopropionate
- Packaging
- 25g
- Price
- $2496
- Updated
- 2021/12/16
Ambeed
- Product number
- A162189
- Product name
- Ethyl3-cyclopentyl-3-oxopropanoate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $22
- Updated
- 2021/12/16
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3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Uses
Ethyl 3-cyclopentyl-3-oxopropionate can be used as a pharmaceutical synthesis intermediate.
Synthesis
4524-93-0
24922-00-7
6a) A hexane solution of 2.4 M n-butyllithium (92.0 mL, 230 mmol) was slowly added dropwise to a solution containing monoethyl malonate (13.6 mL, 115 mmol) and a catalytic amount of 2,2'-bipyridine at -55 to -65 °C. After the dropwise addition, cyclopentanecarbonyl chloride (7.0 mL, 58 mmol) was added in batches. The reaction mixture was gradually warmed to room temperature with stirring and subsequently poured into a mixture of 1N aqueous hydrochloric acid solution and ether. The organic layer was separated, washed three times with saturated sodium bicarbonate solution, dried over anhydrous magnesium sulfate, concentrated and then purified by silica gel column chromatography (eluent: 0-5% ethyl acetate in hexane solution with gradient elution) to afford ethyl 3-cyclopentyl-3-oxopropanoate (9.50 g, 89% yield).1H-NMR (400 MHz, DMSO-d6) δ 4.06 (q, J = 7 Hz. 2H), 3.60 (s, 2H), 2.99-2.91 (m, 1H), 1.78-1.47 (m, 8H), 1.15 (t, J = 7 Hz, 3H).
References
[1] Patent: US2008/96921, 2008, A1. Location in patent: Page/Page column 42
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 17, p. 3186 - 3201
3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER manufacturers
Career Henan Chemical Co
- Product
- 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER 24922-00-7
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 500g； 1kg; 25kg
- Release date
- 2020-01-10
Career Henan Chemical Co
- Product
- 3-CYCLOPENTYL-3-OXO-PROPIONIC ACID ETHYL ESTER 24922-00-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-20
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