Teicoplanin A3-1

Product Name: Teicoplanin A3-1
CAS No.: 93616-27-4
Chemical Name: Teicoplanin A3-1
Synonyms: L 17054;Teicoplanin A3-1;Teicoplanin A3-1 DISCONTINUED. Please see T015500;34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-ristomycinAaglycone;Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-
CBNumber: CB62436968
Molecular Formula: C72H68Cl2N8O28
Formula Weight: 1564.25
MOL File: 93616-27-4.mol

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Teicoplanin A3-1 Property

Density: 1.80±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in ethanol;Soluble in methanol;Soluble in DMSO;Soluble in dimethyl formamide
form: solid
pka: 2.88±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20193
Product name: Teicoplanin A3-1
Purity: ≥98%
Packaging: 1mg
Price: $242
Updated: 2024/03/01

Cayman Chemical

Product number: 20193
Product name: Teicoplanin A3-1
Purity: ≥98%
Packaging: 5mg
Price: $846
Updated: 2024/03/01

ApexBio Technology

Product number: C4943
Product name: TeicoplaninA3-1
Packaging: 5mg
Price: $966
Updated: 2021/12/16

ApexBio Technology

Product number: C4943
Product name: TeicoplaninA3-1
Packaging: 1mg
Price: $276
Updated: 2021/12/16

AK Scientific

Product number: 2702CW
Product name: TeicoplaninA3-1
Packaging: 1mg
Price: $368
Updated: 2021/12/16

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Teicoplanin A3-1 Chemical Properties,Usage,Production

Uses

Teicoplanin A3-1 is a minor polar analogue of a family of lipoglycopeptides produced by Actinoplanes teichomyceticus. Teicoplanins possess potent broad spectrum antibiotic activity against Gram positive bacteria, including MRSA and E. faecalis. Teicoplanin A3-1 is the common degradation product of teicoplanins A2-1 to 5, resulting from cleavage of the lipoaminoglycoside substituents.

Uses

Teicoplanin A3-1 is an antibiotic against Gram positive bacteria.

Definition

ChEBI: A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its alpha-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido- -deoxy-beta-D-glucoside.

Biological Activity

teicoplanin a3-1, also known as antibiotic l 17054, is a glycopeptide antibiotic derived from actinoplanes teichomyceticus and produces a potent broad spectrum antibiotic activity against gram-positive bacteria.teicoplanin a3-1 is a common degradation product of teicoplanins a2-1 to 5, which results from cleavage of the lipoaminoglycoside substituents. teicoplanins are glycopeptide antibiotics produced by a. teichomyceticus which are effective against gram-positive bacteria, including methicillin-resistant staphylococcus aureus (mrsa) and e. faecalis. as an antibiotic complex, teicoplanin consists of five closely related factors, t-a2-1, 2, 3, 4 and 5 and a more polar factor, t-a3-1. additionally, as a glycopeptide antibiotic belonging to the same family as vancomycin, teicoplanin blocks cell wall synthesis in bacillus subtilis, which is accompanied by an intracellular accumulation of udp-n-acetylmuramyl-pentapetide [1]. due to the greater antibacterial activity of teicoplanin than other agents, it has been thoroughly studied as a β-1actamase-resistant agent for the treatment of human infections caused by streptococci and staphylococci, including enterococci [2].

References

[1]. somma, s., gastaldo, l., & corti, a. teicoplanin, a new antibiotic from actinoplanes teichomyceticus nov. sp. antimicrobial agents and chemotherapy. 1984; 26(6): 917-923.
[2]. traina, g., & bonati, m. pharmacokinetics of teicoplanin in man after intravenous administration. journal of pharmacokinetics and biopharmaceutics. 1984;12(2): 119-128.

Teicoplanin A3-1 Preparation Products And Raw materials

Raw materials

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Teicoplanin A3-1 Suppliers

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93616-27-4, Teicoplanin A3-1Related Search:

Teicoplanin

Teicoplanin A3-1

L 17054

Ristomycin A aglycone, 34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-

Teicoplanin A3-1 DISCONTINUED. Please see T015500

34-O-[2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-22,31-dichloro-7-demethyl-64-O-demethyl-19-deoxy-42-O-α-D-mannopyranosyl-ristomycinAaglycone

93616-27-4

C72H68Cl2N8O28