2,2-Dimethyl-1,3-cyclopentanedione
- Product Name
- 2,2-Dimethyl-1,3-cyclopentanedione
- CAS No.
- 3883-58-7
- Chemical Name
- 2,2-Dimethyl-1,3-cyclopentanedione
- Synonyms
- 2,2-Dimethyl-1,3-cyclopentanedione;1,3-Cyclopentanedione, 2,2-dimethyl-
- CBNumber
- CB62444260
- Molecular Formula
- C7H10O2
- Formula Weight
- 126.15
- MOL File
- 3883-58-7.mol
2,2-Dimethyl-1,3-cyclopentanedione Property
- Melting point:
- 46-47 °C
- Boiling point:
- 213.4±23.0 °C(Predicted)
- Density
- 1.050±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T215899
- Product name
- 2,2-DIMETHYL-1,3-CYCLOPENTANEDIONE
- Purity
- AldrichCPR
- Packaging
- 5MG
- Price
- $32.7
- Updated
- 2026/04/30
- Product number
- 1717CA
- Product name
- 2,2-Dimethyl-1,3-cyclopentanedione
- Packaging
- 250mg
- Price
- $168
- Updated
- 2021/12/16
- Product number
- AS440744
- Product name
- 2,2-Dimethyl-1,3-cyclopentanedione
- Purity
- 97%
- Packaging
- 250mg
- Price
- $79
- Updated
- 2021/12/16
- Product number
- A124615
- Product name
- 2,2-Dimethyl-1,3-cyclopentanedione
- Purity
- 97%
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- AS440744
- Product name
- 2,2-Dimethyl-1,3-cyclopentanedione
- Purity
- 97%
- Packaging
- 1g
- Price
- $198
- Updated
- 2021/12/16
2,2-Dimethyl-1,3-cyclopentanedione Chemical Properties,Usage,Production
Synthesis Reference(s)
The Journal of Organic Chemistry, 48, p. 1362, 1983 DOI: 10.1021/jo00156a046
Synthesis
765-69-5
74-88-4
3883-58-7
The reaction was carried out according to the literature method (Agosta, WC; Smith, AB J. Org. Chem. 1970, 35, 3856) using 2-methyl-1,3-cyclopentanedione (10.025 g, 89.4 mmol) and iodomethane (6.0 mL, 96.4 mmol). The above mixture was mixed with a water (25 mL)/dioxane (75 mL) solution of KOH (5.097 g, 90.8 mmol) and heated to reflux for 5 hours. Subsequently, a water (5 mL)/dioxane (15 mL) solution of KOH (2 g) and iodomethane (2.4 mL) was added and refluxing was continued for 3 hours. The reaction mixture was stirred overnight at room temperature. The following morning, a solution of KOH (2 g) and iodomethane (2.4 mL) in water (5 mL)/dioxane (15 mL) was added again and heated to reflux for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and extracted with ether (1 x 100 mL, 3 x 75 mL). The ether extracts were combined, and the residue obtained after evaporation was mixed with 10% HCl (50 mL) and heated to boiling in an oil bath at 120°C (about 15 min). After cooling to room temperature, it was neutralized with saturated NaHCO3 solution (150 mL) and then extracted with dichloromethane (4 x 75 mL). The dichloromethane solutions were combined, dried over MgSO4, filtered and evaporated to afford the brown oily product 2,2-dimethylcyclopentane-1,3-dione (10.474 g, 83 mmol, 93% yield), which could be used in the next reaction without further purification.
References
[1] Patent: US2004/157901, 2004, A1. Location in patent: Page 10
[2] Patent: US9334262, 2016, B2. Location in patent: Page/Page column 62
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 24, p. 5721 - 5726
[4] Advanced Synthesis and Catalysis, 2016, vol. 358, # 9, p. 1392 - 1397
[5] Organic Letters, 2000, vol. 2, # 7, p. 933 - 936
2,2-Dimethyl-1,3-cyclopentanedione Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,2-Dimethyl-1,3-cyclopentanedione manufacturers
- Product
- 2,2-Dimethyl-1,3-cyclopentanedione 3883-58-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-15