7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE

Product Name: 7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE
CAS No.: 879-56-1
Chemical Name: 7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE
Synonyms: 1,2,3,4-Tetrahydro-7-methoxyquinolone;2,3-dihydro-7-methoxy-4(1H)-Quinolinone;7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE;7-methoxy-2,3-dihydro-1h-quinolin-4-one;4(1H)-Quinolinone, 2,3-dihydro-7-methoxy-;7-methoxy-1,2,3,4-tetrahydroquinolin-4-one
CBNumber: CB62446385
Molecular Formula: C10H11NO2
Formula Weight: 177.2
MOL File: 879-56-1.mol

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7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
Appearance: Off-white to pink Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B593428
Product name: 7-methoxy-2,3-dihydroquinolin-4(1H)-one
Packaging: 50mg
Price: $220
Updated: 2021/12/16

Ark Pharm

Product number: P000476162
Product name: 7-Methoxy-2,3-dihydroquinolin-4(1H)-one
Purity: 95+%
Packaging: 100mg
Price: $173
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0986560
Product name: 1,2,3,4-TETRAHYDRO-7-METHOXYQUINOLONE
Purity: 95.00%
Packaging: 5MG
Price: $502.9
Updated: 2021/12/16

Ark Pharm

Product number: P000476162
Product name: 7-Methoxy-2,3-dihydroquinolin-4(1H)-one
Purity: 95+%
Packaging: 1g
Price: $649
Updated: 2021/12/16

AK Scientific

Product number: 0402CN
Product name: 7-Methoxy-2,3-dihydroquinolin-4(1H)-one
Packaging: 2.5g
Price: $1408
Updated: 2021/12/16

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7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE Chemical Properties,Usage,Production

Synthesis

3334-67-6

879-56-1

Compounds 1-3 (CAS: 3334-67-6) (40.0 g, 20.5 mmol) were taken as raw material and mixed with polyphosphoric acid (PPA) (100 mL) and the reaction was carried out with mechanical stirring at 90 °C for 3 hours. Upon completion of the reaction, the mixture was cooled to 60 °C and ice water (50 mL) was slowly added under stirring for 30 min. Subsequently, the mixture was extracted using ethyl acetate (EtOAc) (120 mL × 3). The organic phases were combined, washed sequentially with water (40 mL) and brine (40 mL), and then dried with anhydrous Na2SO4. After removal of the solvent under reduced pressure, the residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol = 100/1 (v/v)) to afford the target product, 7-methoxy-2,3-dihydroquinolin-4(1H)-one (Compounds 1-4) (18 g, 50% yield), as a yellow solid. lc-MS (ESI): m/z 178 [M + H]+.

References

[1] Synthesis, 2006, # 11, p. 1791 - 1802
[2] Patent: WO2012/58125, 2012, A1. Location in patent: Page/Page column 112; 113
[3] Patent: WO2007/3934, 2007, A2. Location in patent: Page/Page column 240
[4] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 7, p. 1003 - 1008

7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE Suppliers

China 25 Germany 1 United States 1 Global 27

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
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Synchem OHG

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LABTER PHARMATECH(BEIJING) CO.,LTD

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Aikon International Limited

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SHANGHAI FDC-CHEMICAL CO.,LTD

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Fan De(Beijing) Biotechnology Co., Ltd.

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Chengdu Feibai Pharmaceutical Co., Ltd.

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879-56-1, 7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONERelated Search:

7-METHOXY-1-INDANECARBOXYLIC ACID 7-METHOXY-2,3-DIHYDRO-BENZOFURAN-3-YLAMINE HYDROCHLORIDE 7-methoxy-2,3-dihydro-1H-inden-1-amine 7-METHOXY-2,3-DIHYDRO-1H-INDEN-1-AMINE HYDROCHLORIDE 7-METHOXY-3,3-DIMETHYL-2,3-DIHYDRO-1H-INDEN-1-ONE 7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE AURORA KA-4644 AURORA KA-4075 AURORA KA-4074 7-METHOXY-1-[(4-METHYLPHENYL)SULFONYL]-2,3-DIHYDROQUINOLIN-4(1H)-ONE AURORA KA-4752 AURORA KA-4506 AURORA KA-4056 AURORA KA-4057 AURORA KA-3681 AURORA KA-4058 AURORA KA-4062 AURORA KA-4645

7-METHOXY-2,3-DIHYDROQUINOLIN-4(1H)-ONE

1,2,3,4-Tetrahydro-7-methoxyquinolone

2,3-dihydro-7-methoxy-4(1H)-Quinolinone

7-methoxy-1,2,3,4-tetrahydroquinolin-4-one

4(1H)-Quinolinone, 2,3-dihydro-7-methoxy-

7-methoxy-2,3-dihydro-1h-quinolin-4-one

879-56-1