(4-METHYL-1-NAPHTHALENE)BORONIC ACID

Product Name: (4-METHYL-1-NAPHTHALENE)BORONIC ACID
CAS No.: 103986-53-4
Chemical Name: (4-METHYL-1-NAPHTHALENE)BORONIC ACID
Synonyms: AKOS BRN-0320;RARECHEM AH PB 0103;1-Borono-4-methylnaphthalene;4-Methyl-1-naphthylboronic Acid;(4-Methylnaphth-1-yl)boronic acid;1-Methylnaphthalene-4-boronic acid;4-METHYLNAPHTHALENE-1-BORONIC ACID;(4-Methyl-1-naphtalene)boronic acid;4-methylnaphthalen-1-ylboronic acid;(4-METHYL-1-NAPHTHALYL)BORONIC ACID
CBNumber: CB6244747
Molecular Formula: C11H11BO2
Formula Weight: 186.01
MOL File: 103986-53-4.mol

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(4-METHYL-1-NAPHTHALENE)BORONIC ACID Property

Melting point:: 229-235 °C (dec.)(lit.)
Boiling point:: 386.3±35.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 8.95±0.30(Predicted)
form: Powder
color: White to off-white
CAS DataBase Reference: 103986-53-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29319090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 521450
Product name: 4-Methyl-1-naphthaleneboronic acid
Purity: ≥95%
Packaging: 10g
Price: $236
Updated: 2022/05/15

TCI Chemical

Product number: M2457
Product name: 4-Methyl-1-naphthaleneboronic Acid (contains varying amounts of Anhydride)
Packaging: 1g
Price: $41
Updated: 2025/07/31

TCI Chemical

Product number: M2457
Product name: 4-Methyl-1-naphthaleneboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $161
Updated: 2025/07/31

TRC

Product number: M330898
Product name: 4-Methyl-1-naphthaleneboronic acid
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Chem-Impex

Product number: 40087
Product name: 4-Methyl-1-naphthaleneboronicacid,95-105%(Assaybytitration)
Purity: 95-105%(Assaybytitration)
Packaging: 1G
Price: $30.24
Updated: 2021/12/16

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(4-METHYL-1-NAPHTHALENE)BORONIC ACID Chemical Properties,Usage,Production

Chemical Properties

Off-white powder

Uses

Reactant for Suzuki-Miyaura coupling.

Synthesis

5419-55-6

6627-78-7

103986-53-4

3.4. Synthesis of 4-methyl-1-naphthalenylboronic acid: Dissolve 1-bromo-4-methylnaphthalene (1.5 g, 6.78 mmol) in anhydrous ethyl ether (200 mL) and cool the solution to -78°C. Slowly add n-BuLi (1.7 M hexane solution, 10 mL), keeping the temperature at -78 °C. After addition, the reaction mixture was allowed to gradually warm to room temperature and stirred for 2 hours. The reaction mixture was again cooled to -78 °C and a solution of triisopropyl borate (4 g, 4.91 mL, 21.27 mmol) in ether (20 mL) was quickly added. After stirring at -78 °C for 30 min, it was brought to room temperature and continued stirring for 15 hours. Upon completion of the reaction, 100 mL of 2M HCl was added and the milky white emulsion was observed to gradually become clear. The ether layer was separated and the aqueous layer was extracted with ether (3 x 100 mL). All ether extracts were combined, dried with MgSO4, and the solvent was removed by rotary evaporation. The residual solid was recrystallized with hot CH2Cl2 to give a white solid product. Yield: 95%.1H NMR (300 MHz, CD2Cl2): δ 9.33 (d, J = 9.3 Hz, 1H), 8.59 (d, J = 7.0 Hz, 1H), 8.16 (d, J = 9.5 Hz, 1H), 7.65 (dd, 2H), 7.54 (d, J = 7.6 Hz, 1H), 2.82 (s, 3H). 13C NMR (75 MHz, CD2Cl2): δ 140.3, 137.5, 132.8, 132.3, 128.6, 126.5, 126.3, 125.9, 125.7, 124.6, 19.5; MS (CI, CH4): m/z calcd for C11H11BO2: 186.1; found : 186.1 [M+]. Calcd for C11H11BO2-H2O: C, 64.75; H, 6.42. Found: C, 62.91; H, 5.64.

References

[1] Tetrahedron, 2012, vol. 68, # 46, p. 9371 - 9375,5
[2] Tetrahedron,
[3] Patent: CN107814795, 2018, A. Location in patent: Paragraph 0028; 0030
[4] Patent: CN107973777, 2018, A. Location in patent: Paragraph 0042; 0045; 0046
[5] Patent: CN108129453, 2018, A. Location in patent: Paragraph 0041; 0042; 0045; 0046

(4-METHYL-1-NAPHTHALENE)BORONIC ACID Preparation Products And Raw materials

Raw materials

1-BROMO-2-METHYLNAPHTHALENE TRIPROPYL BORATE Tetrahydrofuran Diethyl ether n-Butyllithium

Preparation Products

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(4-METHYL-1-NAPHTHALENE)BORONIC ACID Suppliers

Americas 1 Belgium 3 China 98 Europe 1 France 3 Germany 9 India 4 Italy 1 Japan 1 Russia 1 Switzerland 1 The Netherlands 1 United Kingdom 5 United States 32 Global 161

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View Lastest Price from (4-METHYL-1-NAPHTHALENE)BORONIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: (4-METHYL-1-NAPHTHALENE)BORONIC ACID 103986-53-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: (4-METHYL-1-NAPHTHALENE)BORONIC ACID 103986-53-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: (4-METHYL-1-NAPHTHALENE)BORONIC ACID 103986-53-4
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: JD 812
Release date: 2019-09-02

103986-53-4, (4-METHYL-1-NAPHTHALENE)BORONIC ACIDRelated Search:

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4-Methyl-1-naphthaleneboronic acid - [M4420]

103986-53-4

CH3C10H6BOH2

C11H11BO2

BORONIC ACID

Organometallic Reagents

Aryl

Boronic Acids and Derivatives

Boronic Acids

Boronic Acids and Derivatives

Aryl

blocks

BoronicAcids