ChemicalBook > CAS DataBase List > 2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER

2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER

Product Name: 2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER
CAS No.: 863578-21-6
Chemical Name: 2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER
Synonyms: 25G 100G 500G;2-Amino-4-chlorophenyl boronic acid;2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER;5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl);5-chloro-2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)aniline;Benzenamine, 5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber: CB62459763
Molecular Formula: C12H17BClNO2
Formula Weight: 253.53
MOL File: 863578-21-6.mol

Less

2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER Property

Boiling point:: 363.6±32.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
pka: 2.84±0.11(Predicted)
Appearance: Off-white to light brown Solid

Less

Safety

HS Code: 2931900090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: A617568
Product name: 2-Amino-4-chlorophenylboronicacidpinacolester
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A617568
Product name: 2-Amino-4-chlorophenylboronicacidpinacolester
Packaging: 25mg
Price: $55
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA160776
Product name: 2-Amino-4-chlorophenylboronic acid pinacol ester
Packaging: 50mg
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA160776
Product name: 2-Amino-4-chlorophenylboronic acid pinacol ester
Packaging: 100mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA160776
Product name: 2-Amino-4-chlorophenylboronic acid pinacol ester
Packaging: 500mg
Price: $325
Updated: 2021/12/16

Less

2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER Chemical Properties,Usage,Production

Synthesis

823-57-4

25015-63-8

863578-21-6

Step 1: Preparation of 5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline To a solution of 2-bromo-5-chloroaniline (20.0 g, 96.9 mmol) in 1,4-dioxane (200 ml) was sequentially added triethylamine (54.0 ml, 487 mmol) and [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride dichloromethane complex (3.96 g, 4.84 mmol) under nitrogen protection. Subsequently, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane (42.3 ml, 290 mmol) was slowly added dropwise. The reaction mixture was stirred at 100 °C for 10.5 hours. After completion of the reaction, the mixture was cooled to room temperature and filtered through diatomaceous earth. The filtrate was quenched by dropwise addition of methanol (25 ml) at 0°C. The solvent was removed by concentration under reduced pressure and the resulting crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 20:1) to afford the target product 5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (16.5 g, 65% yield). 1H-NMR (400 MHz, DMSO-d6): δ (ppm) 7.28 (1H, d, J=6.0 Hz), 6.59 (1H, d, J=1.2 Hz), 6.43 (1H, dd, J=6.3,1.5 Hz), 5.70 (2H, s), 1.24 (12H, s).

References

[1] Patent: EP1719773, 2006, A1. Location in patent: Example 1-10

2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER Suppliers

China 62 India 1 United Kingdom 1 United States 6 Global 70

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Changzhou Chemscaler Pharmtech Co., Ltd.

Tel: 0519-81096292 15312577869
Email: chemscaler@yahoo.com.cn
Country: China
ProdList: 311
Advantage: 60

Zhengzhou HSH Science & Technology Co., Ltd.

Tel: 0371-55932928 18937192232
Fax: 0086-0371-55932928
Email: 1282296214@qq.com
Country: China
ProdList: 498
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Changsha Luxing Bio-Chem Technology Co., Ltd.

Tel: 0731-88827538 15873153880
Fax: 0731-88827238
Email: luxingbc@126.com
Country: China
ProdList: 1999
Advantage: 65

Shanghai Rong Lin Medical Technology Co., Ltd.

Tel: 18602194589
Email: lincy-110@163.com
Country: China
ProdList: 863
Advantage: 58

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Hangzhou Milestone Pharmtech Co., Ltd.

Tel: 0571-82896630 18969958410
Email: sales_hz@milestonepharmtech.com
Country: China
ProdList: 4895
Advantage: 55

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Zhengzhou AiXi Technology Co., Ltd.

Tel: 0371-56787280 13137706083
Fax: -
Email: m18539565376@163.com
Country: China
ProdList: 970
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Changzhou Pesan Chemical Co.,Ltd.

Tel: +8615921661320
Email: zhangk@pesanchem.com
Country: China
ProdList: 999
Advantage: 58

Nanjing holy chemical co., LTD

Tel: 19951936396
Email: 1815156226@qq.com
Country: China
ProdList: 2947
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Medicil Biomedical Co., Ltd.

Tel: 021-50822001
Email: marketing@medicilon.com.cn
Country: China
ProdList: 1152
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 13316949107 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 9564
Advantage: 58

Labnetwork lnc.

Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Country: China
ProdList: 19987
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

LEADMEDPHARM CO.,LTD

Tel: 13674959855 13674959855
Email: sales@synthontech.com
Country: China
ProdList: 3035
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Richest Group Ltd

Tel: 18017061086
Email: oled@richest-group.com
Country: CHINA
ProdList: 5600
Advantage: 58

Antai Fine Chemical Technology Co.,Limited

Tel: 18503026267
Email: info@antaichem.com
Country: CHINA
ProdList: 9636
Advantage: 58

Neostar United (Changzhou) Industrial Co., Ltd.

Tel: +86-0519-85551759 +8613506123987
Fax: +0086-519-85557389
Email: marketing1@neostarunited.com
Country: China
ProdList: 8830
Advantage: 58

Zhengzhou Alpha Chemical Co. LTD

Tel: 0371-0371-53732842 13383863444
Fax: QQ：3002612166
Email: 3002612166@qq.com
Country: China
ProdList: 9996
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Chino Pharmaceutical Technology Co., Ltd

Tel: 021-021-51557188 15901710861
Fax: QQ: 569058060
Email: sales@channelpharm.com
Country: China
ProdList: 1228
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 18130062233
Email: 3362556465@qq.com
Country: China
ProdList: 8100
Advantage: 58

Suzhou Daolan Biomedical Technology Co., Ltd.

Tel: 15952404857
Email: sales@dolanpharm.com
Country: China
ProdList: 2919
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Suzhou Qihang Biotechnology Co., Ltd

Tel: 18151111370
Email: 1046215251@qq.com
Country: China
ProdList: 8718
Advantage: 58

PharmaBlock Sciences (Nanjing), Inc.

Tel: 4000255188
Email: sales@pharmablock.com
Country: China
ProdList: 7268
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 18736790110;
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 50000
Advantage: 58

Shanghai Fengji Pharmaceutical Technology Co., Ltd

Tel: 15555063509
Email: 153666767@qq.com
Country: China
ProdList: 2751
Advantage: 58

Shanghai Fengman Biopharmaceutical Co., Ltd

Tel: 18949985122 18949985122;
Email: 421774967@qq.com
Country: China
ProdList: 368
Advantage: 58

Henan Vcommend Consultrading Co., Ltd.

Tel: 13393721940
Email: sales@vcommend.com
Country: China
ProdList: 9963
Advantage: 58

Hangzhou Bingochem Co., Ltd.

Tel: 0571-8512-5372
Email: sales@bingochem.com
Country: China
ProdList: 21669
Advantage: 58

Shaoyuan Technology (Shanghai) Co., Ltd.

Tel: 021-50795510 4000665055
Email: sy-c5@accelachem.com
Country: China
ProdList: 10000
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-81136151 17392212881
Email: 1095@dideu.com
Country: China
ProdList: 9984
Advantage: 58

Shanghai Troedsson Technology Co., LTD

Tel: 18117455885
Email: qihongchem@163.com
Country: China
ProdList: 9092
Advantage: 58

Less

View Lastest Price from 2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER 863578-21-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-21

Career Henan Chemical Co

Product: 2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER 863578-21-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%-100%
Supply Ability: 1
Release date: 2018-08-12

863578-21-6, 2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTERRelated Search:

3-AMINO-4-CHLOROPHENYLBORONIC ACID, PINACOL ESTER (2-AMINO-4-CARBOXY)BENZENEBORONIC ACID HYDROCHLORIDE 3-Amino-5-carboxylphenylboronic acid 4-Amino-3-chlorophenylboronic acid, pinacol ester 4-Amino-2-chlorophenylboronic acid, pinacol ester 3-AMINO-4-CHLOROPHENYLBORONIC ACID 2-AMINO-5-CHLOROPHENYLBORONIC ACID, PINACOL ESTER (3-AMINO-4-CHLOROPHENYL)BORONIC ACID HYDROCHLORIDE

2-AMINO-4-CHLOROPHENYL BORONIC ACID PINACOL ESTER

2-Amino-4-chlorophenyl boronic acid

5-chloro-2-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)aniline

25G 100G 500G

5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)

Benzenamine, 5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

863578-21-6