ChemicalBook > CAS DataBase List > 6-Bromo-3-chloropyrazin-2-amine

6-Bromo-3-chloropyrazin-2-amine

Product Name: 6-Bromo-3-chloropyrazin-2-amine
CAS No.: 1082843-72-8
Chemical Name: 6-Bromo-3-chloropyrazin-2-amine
Synonyms: 6-Bromo-3-chloro-2-pyrazinamine;6-Bromo-3-chloropyrazin-2-amine;2-Amino-3-chloro-6-bromopyrazine;2-Amino-6-bromo-3-chloropyrazine;2-Pyrazinamine, 6-bromo-3-chloro-;3-Chloro-6-bromopyrazin-2-ylamine
CBNumber: CB62471576
Molecular Formula: C4H3BrClN3
Formula Weight: 208.44
MOL File: 1082843-72-8.mol

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6-Bromo-3-chloropyrazin-2-amine Property

Boiling point:: 288℃
Density: 1.960
Flash point:: 128℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 0.05±0.10(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C4H3BrClN3/c5-2-1-8-3(6)4(7)9-2/h1H,(H2,7,9)
InChIKey: LYMPGCBRUNBZJX-UHFFFAOYSA-N
SMILES: C1(N)=NC(Br)=CN=C1Cl

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific

Product number: X8875
Product name: 6-Bromo-3-chloropyrazin-2-amine
Packaging: 250mg
Price: $120
Updated: 2021/12/16

Matrix Scientific

Product number: 073737
Product name: 6-Bromo-3-chloropyrazin-2-amine
Purity: 95+%
Packaging: 1g
Price: $240
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0367742
Product name: 6-BROMO-3-CHLOROPYRAZIN-2-AMINE
Purity: 95.00%
Packaging: 5MG
Price: $503.15
Updated: 2021/12/16

Ambeed

Product number: A358442
Product name: 6-Bromo-3-chloropyrazin-2-amine
Purity: 97%
Packaging: 10g
Price: $543
Updated: 2021/12/16

Alichem

Product number: 1082843728
Product name: 6-Bromo-3-chloropyrazin-2-amine
Packaging: 10g
Price: $621.3
Updated: 2021/12/16

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6-Bromo-3-chloropyrazin-2-amine Chemical Properties,Usage,Production

Synthesis

1082843-70-6

1082843-72-8

General procedure for the synthesis of 3-chloro-6-bromopyrazin-2-amine from 3,5-dibromo-2-chloropyrazine: 3,5-dibromo-2-chloropyrazine (50.0 g, 184 mmol) and concentrated ammonia (150 mL) were added to a 250 mL sealed tube. The reaction mixture was stirred at 100 °C overnight. Upon completion of the reaction, it was cooled to room temperature and the resulting solid product was collected by filtration. The resulting solid was dried under reduced pressure in an oven to afford 3-chloro-6-bromopyrazin-2-amine as a gray solid (28.0 g, 66% yield), which could be used in subsequent reactions without further purification.

References

[1] Patent: US2014/364414, 2014, A1. Location in patent: Paragraph 0945; 0954-0955
[2] Patent: US2009/286798, 2009, A1. Location in patent: Page/Page column 27

6-Bromo-3-chloropyrazin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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1082843-72-8