ChemicalBook > CAS DataBase List > KR-12 (human)
KR-12 (human)
- Product Name
- KR-12 (human)
- CAS No.
- 1218951-51-9
- Chemical Name
- KR-12 (human)
- Synonyms
- KR-12 (human);KR-12 amide (human);KR-12 (human) trifluoroacetate salt;Antibacterial Protein LL-37 amide (human) (18-29);LL-37 (18-29), CAMP (18-29), Antibacterial Protein;H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2;Antibacterial Protein LL-37 aMide (huMan) (18-29), LL-37 (18-29), LL37 (18-29), CAMP (18-29);KR-12 amide (human)/Antibacterial Protein LL-37 amide (human) (18-29), LL-37 (18-29), LL37 (18-29), CAMP (18-29);L-Lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-L-argininamide;L-Argininamide, L-lysyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-arginyl-L-isoleucyl-L-lysyl-L-α-aspartyl-L-phenylalanyl-L-leucyl-
- CBNumber
- CB62476955
- Molecular Formula
- C71H127N25O15
- Formula Weight
- 1570.92658
- MOL File
- 1218951-51-9.mol
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KR-12 (human) Property
- Density
- 1.40±0.1 g/cm3(Predicted)
- pka
- 4.19±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- Sequence
- H-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-NH2
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KR-12 (human) Chemical Properties,Usage,Production
Uses
KR-12 human is an active segment of LL-37, which exhibits antimicrobial activity against gram-negative bacteria. KR-12 human inhibits E. coli K-12 with MIC of 66 μM[1].
References
[1] Epand RF, et al., Lipid segregation explains selective toxicity of a series of fragments derived from the human cathelicidin LL-37. Antimicrob Agents Chemother. 2009 Sep;53(9):3705-14. DOI:10.1128/AAC.00321-09
KR-12 (human) Preparation Products And Raw materials
Raw materials
Preparation Products
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KR-12 (human) Suppliers
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- 21-61263452 13641803416
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- 86-21-61263399
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- China
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- 025-58361106-805 15951641583
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