ChemicalBook > CAS DataBase List > 5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
- Product Name
- 5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
- CAS No.
- 936500-94-6
- Chemical Name
- 5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide
- Synonyms
- elinogrel;PRT 060128;P2Y Receptor,inhibit,PRT 060128,Elinogrel,Inhibitor,PRT-060128;5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(MethylaMino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]aMino]carb;5-Chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide;5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide;2-Thiophenesulfonamide, 5-chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-
- CBNumber
- CB62484752
- Molecular Formula
- C20H15ClFN5O5S2
- Formula Weight
- 523.95
- MOL File
- 936500-94-6.mol
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5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Property
- Density
- 1.651
- storage temp.
- Store at -20°C
- solubility
- DMSO: 100 mM
- form
- A solid
- pka
- 4.42±0.10(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 25976
- Product name
- Elinogrel
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $57
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25976
- Product name
- Elinogrel
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $179
- Updated
- 2024/03/01
Tocris
- Product number
- 5316
- Product name
- Elinogrel
- Purity
- ≥97%(HPLC)
- Packaging
- 10
- Price
- $235
- Updated
- 2021/12/16
Tocris
- Product number
- 5316
- Product name
- Elinogrel
- Purity
- ≥97%(HPLC)
- Packaging
- 50
- Price
- $971
- Updated
- 2021/12/16
TRC
- Product number
- E508028
- Product name
- Elinogrel
- Packaging
- 10mg
- Price
- $175
- Updated
- 2021/12/16
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5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Chemical Properties,Usage,Production
Description
Elinogrel is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 23 nM) that inhibits platelet aggregation in a human platelet-rich plasma (hPRP) assay (IC50 = 2.81 nM). It inhibits thrombosis in a mouse model of vascular injury induced by iron (III) chloride (FeCl3) when administered at a dose of 60 mg/kg.
Uses
Elinogrel is a direct acting reversible P2Y12 inhibitor, which shows an antiplatelet effect and platelet reactivity associated with cytochrome P 450 2C19 and 3A5 gene polymorphisms.
storage
Store at -20°C
5-Chloro-N-[[[4-[6-fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide Preparation Products And Raw materials
Raw materials
Preparation Products
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