ChemicalBook > CAS DataBase List > 5-Bromo-3-methyl-7-azaindole

5-Bromo-3-methyl-7-azaindole

Product Name
5-Bromo-3-methyl-7-azaindole
CAS No.
1111637-94-5
Chemical Name
5-Bromo-3-methyl-7-azaindole
Synonyms
5-Bromo-3-methyl-7-azaindole;5-BroMo-3-Methyl-7-azaind...;5-bromo-3-methyl-pyrrolo[2,3-b]pyridine;5-Bromo-3-methyl-1H-pyrrolo[2,3-b]pyridine;3-Bromo-5-methyl-7H-pyrrolo[2,3-b]pyridine;5-bromo-3-methyl-1H-pyrrolo[2,4-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-Methyl-
CBNumber
CB62485542
Molecular Formula
C8H7BrN2
Formula Weight
211.06
MOL File
1111637-94-5.mol
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5-Bromo-3-methyl-7-azaindole Property

Density 
1.654±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
13.22±0.40(Predicted)
Appearance
Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B808408
Product name
5-Bromo-3-methyl-1H-pyrrolo[2,3-b]pyridine
Packaging
50mg
Price
$90
Updated
2021/12/16
TRC
Product number
B808408
Product name
5-Bromo-3-methyl-1H-pyrrolo[2,3-b]pyridine
Packaging
100mg
Price
$130
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-88
Product name
3-Bromo-5-methyl-7H-pyrrolo[2,3-b]pyridine
Packaging
250mg
Price
$150
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0366951
Product name
5-BROMO-3-METHYL-1H-PYRROLO[2,3-B]PYRIDINE
Purity
95.00%
Packaging
250MG
Price
$308.7
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-88
Product name
3-Bromo-5-methyl-7H-pyrrolo[2,3-b]pyridine
Packaging
1g
Price
$450
Updated
2021/12/16
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5-Bromo-3-methyl-7-azaindole Chemical Properties,Usage,Production

Synthesis

1620574-95-9

1111637-94-5

5-Bromo-3-methyl-1-toluenesulfonyl-1H-pyrrolo[2,3-B]pyridine (35 g, 96.2 mmol) was used as a raw material and dissolved in methanol (200 mL). To this solution, 6N sodium hydroxide solution (200 μL) was slowly added, followed by heating the reaction mixture to reflux and maintaining the reaction for 2 hours. After completion of the reaction, methanol was removed by vacuum concentration. The pH of the reaction mixture was adjusted to 7 with citric acid, followed by filtration of the precipitated solid. The solid was washed several times with deionized water and dried to give the target product 5-bromo-3-methyl-1H-pyrrolo[2,3-b]pyridine as a yellow solid (20 g, 98.5% yield). The product was confirmed by NMR hydrogen spectroscopy (400 MHz, DMSO-d6) with chemical shifts of δ11.462 (s, 1H), 8.134 (s, 1H), 8.045 (s, 1H), 7.210 (s, 1H), and 2.135 (s, 3H), respectively.

References

[1] Patent: WO2014/111496, 2014, A1. Location in patent: Page/Page column 99
[2] Patent: WO2016/142310, 2016, A1. Location in patent: Page/Page column 65

5-Bromo-3-methyl-7-azaindole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Bromo-3-methyl-7-azaindole Suppliers

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1111637-94-5, 5-Bromo-3-methyl-7-azaindoleRelated Search:


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