Incyclinide

Product Name: Incyclinide
CAS No.: 15866-90-7
Chemical Name: Incyclinide
Synonyms: COL 3;CMT 3;Metastat;NSC 683551;Incyclinide;Incyclinide (CMT-3);Incyclinide, 10 mM in DMSO;INCYCLINIDE (CMT-3, COL-3);COL 3,CMT 3,Matrix metalloproteinases,inhibit,Inhibitor,Incyclinide,CMT3,COL3,MMP;(4aS,5aR,12aS)-3,10,12,12a-Tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
CBNumber: CB62498809
Molecular Formula: C19H17NO7
Formula Weight: 371.34
MOL File: 15866-90-7.mol

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Incyclinide Property

Melting point:: 228-231 °C
Boiling point:: 752.8±60.0 °C(Predicted)
Density: 1.70±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:100.0(Max Conc. mg/mL);269.29(Max Conc. mM)
form: A solid
pka: 4.50±1.00(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 354898
Product name: COL3
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

Usbiological

Product number: 354897
Product name: COL3
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

ChemScene

Product number: CS-7504
Product name: Incyclinide
Purity: 95.70%
Packaging: 50mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-7504
Product name: Incyclinide
Purity: 95.70%
Packaging: 1mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-7504
Product name: Incyclinide
Purity: 95.70%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

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Incyclinide Chemical Properties,Usage,Production

Uses

Treatment of acne, rosacea, and acute respiratory distress syndrome.

Uses

Incyclinide is MMP inhibitor. Potential anti-COVID-19 drugs which which significantly downregulate ACE2 activity.

brand name

Metastat (CollaGenex).

in vivo

Incyclinide inhibits tooth movement in the rat, probably by reducing the number of osteoclasts at the compression side. This might be due to induction of apoptosis in activated osteoclasts or reduced osteoclast migration. Reduced MMP activity by incyclinide might also directly inhibit degradation of the organic bone matrix^[3].

Incyclinide Preparation Products And Raw materials

Raw materials

Preparation Products

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Incyclinide Suppliers

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15866-90-7, IncyclinideRelated Search:

INCYCLINIDE (CMT-3, COL-3)

Incyclinide

2-NaphthacenecarboxaMide,1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-,(4aS,5aR,12aS)-

CMT 3

COL 3

Metastat

NSC 683551

Incyclinide (CMT-3)

COL 3,CMT 3,Matrix metalloproteinases,inhibit,Inhibitor,Incyclinide,CMT3,COL3,MMP

(4aS,5aR,12aS)-3,10,12,12a-Tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

Incyclinide, 10 mM in DMSO

(4AS,5AR,12AS)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-2-NAPHTHACENECARBOXAMIDE

15866-90-7