3,5-dichloropyridazin-4-amine

Uses

Product Name: 3,5-dichloropyridazin-4-amine
CAS No.: 53180-76-0
Chemical Name: 3,5-dichloropyridazin-4-amine
Synonyms: 3,5-dichloropyridazin-4-amine;4-Amino-3,5-dichloropyridazine;4-PyridazinaMine, 3,5-dichloro-;3,5-dichloro-1,4-dihydropyridazin-4-imine;3,5-dichloropyridazin-4-amine ISO 9001：2015 REACH
CBNumber: CB62499275
Molecular Formula: C4H3Cl2N3
Formula Weight: 163.99
MOL File: 53180-76-0.mol

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3,5-dichloropyridazin-4-amine Property

Melting point:: 176-178 °C
Boiling point:: 331.3±37.0 °C(Predicted)
Density: 1.606±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 2.03±0.10(Predicted)
Appearance: Off-white to yellow Solid
InChI: InChI=1S/C4H3Cl2N3/c5-2-1-8-9-4(6)3(2)7/h1H,(H2,7,8)
InChIKey: RPFJGTZUJUOCCL-UHFFFAOYSA-N
SMILES: C1(Cl)=NN=CC(Cl)=C1N

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC

Product number: D438160
Product name: 3,5-Dichloropyridazin-4-amine
Packaging: 50mg
Price: $95
Updated: 2021/12/16

TRC

Product number: D438160
Product name: 3,5-Dichloropyridazin-4-amine
Packaging: 100mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD154571
Product name: 3,5-Dichloropyridazin-4-amine
Packaging: 250mg
Price: $137.5
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-5-95
Product name: 4-Amino-3,5-dichloropyridazine
Packaging: 250mg
Price: $138
Updated: 2021/12/16

AK Scientific

Product number: W6766
Product name: 3,5-Dichloropyridazin-4-amine
Packaging: 250mg
Price: $201
Updated: 2021/12/16

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3,5-dichloropyridazin-4-amine Chemical Properties,Usage,Production

Uses

3,5-dichloropyridazin-4-amine is a heterocyclic derivative, which can be used as a pharmaceutical intermediate and used in pharmaceutical experimental research.

Synthesis

14161-11-6

53180-76-0

General procedure for the synthesis of 4-amino-3,5-dichloropyridazine from 3,4,5-trichloropyridazine: 3,4,5-trichloropyridazine (3,500 mg, 2.73 mmol) was dissolved in a mixture of ethanol (5.5 mL) and ammonium hydroxide (5.5 mL) in a microwave reactor and heated at 120 °C for 25 min. After completion of the reaction, the reaction solution was concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography, and the eluent was a mixed solution of acetone and dichloromethane (acetone volume fraction 0-15%). 4-Amino-3,5-dichloropyridazine was finally obtained in 36% yield (163 mg). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 5.11 (broad peak, 2H), 8.74 (single peak, 1H).LC-MS analysis showed a retention time of Rt = 0.27 min and a mass spectrum m/z 164 [M + H]+.

References

[1] Patent: US2014/171435, 2014, A1. Location in patent: Paragraph 0454; 0455; 0456
[2] Patent: WO2015/189744, 2015, A1. Location in patent: Page/Page column 66
[3] Patent: WO2015/198045, 2015, A1. Location in patent: Page/Page column 97

3,5-dichloropyridazin-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-dichloropyridazin-4-amine Suppliers

China 78 Germany 1 India 1 United Kingdom 2 United States 5 Global 87

Linyi Azelasi Biological Co., Ltd.

Tel: 17753923223
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9ding chemical ( Shanghai) Limited

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SynAsst Chemical.

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Runpharm Technology Limited

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Wuhan Kaymke Chemical Co., Ltd.,

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View Lastest Price from 3,5-dichloropyridazin-4-amine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 3,5-Dichloropyridazin-4-amine 53180-76-0
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-26

Shanghai Rlavie Technology Co ltd

Product: 3,5-dichloropyridazin-4-amine 53180-76-0
Price: US $0.00/KG
Min. Order: 1g
Purity: 98%minHPLC
Supply Ability: 10kgs/month
Release date: 2021-11-05

Dideu Industries Group Limited

Product: 3,5-dichloropyridazin-4-amine 53180-76-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-11-08

53180-76-0, 3,5-dichloropyridazin-4-amineRelated Search:

3,5-dichloropyridazin-4-amine

4-Amino-3,5-dichloropyridazine

4-PyridazinaMine, 3,5-dichloro-

3,5-dichloro-1,4-dihydropyridazin-4-imine

3,5-dichloropyridazin-4-amine ISO 9001：2015 REACH

53180-76-0