2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid

Product Name: 2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid
CAS No.: 856417-64-6
Chemical Name: 2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid
Synonyms: BOC-DL-ASP(OME);Boc-DL-Asp(OMe)-OH;Boc-DL-aspartate 4-methyl ester;2-(tert-butoxycarbonyl)-4-Methoxy-4-oxobutanoic acid;4-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-;2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic 2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid;Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-methyl ester;4-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid;(S)-4-((2-((tert-Butoxycarbonyl))amino)ethyl)(2.4.6-trimethoxybenzyl)amino)-4-oxobutanoic acid
CBNumber: CB62499644
Molecular Formula: C10H17NO6
Formula Weight: 247.25
MOL File: 856417-64-6.mol

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2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid Property

Boiling point:: 411.5±40.0 °C(Predicted)
Density: 1.209±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 3.65±0.23(Predicted)
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-M1479
Product name: 2-(tert-butoxycarbonyl)-4-methoxy-4-oxobutanoicacid
Purity: ≥97.0%
Packaging: 1g
Price: $68
Updated: 2021/12/16

Activate Scientific

Product number: AS37876
Product name: 2-((tert-Butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid
Purity: 95%
Packaging: 250mg
Price: $134
Updated: 2021/12/16

ChemScene

Product number: CS-M1479
Product name: 2-(tert-butoxycarbonyl)-4-methoxy-4-oxobutanoicacid
Purity: ≥97.0%
Packaging: 5g
Price: $200
Updated: 2021/12/16

Activate Scientific

Product number: AS37876
Product name: 2-((tert-Butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid
Purity: 95%
Packaging: 1g
Price: $295
Updated: 2021/12/16

AK Scientific

Product number: Z5195
Product name: 2-((tert-Butoxycarbonyl)amino)-4-methoxy-4-oxobutanoicacid
Packaging: 5g
Price: $317
Updated: 2021/12/16

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2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid Chemical Properties,Usage,Production

Synthesis

1835-51-4

856417-64-6

The general procedure for the synthesis of 2-((tert-butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid from 4-methyl DL-aspartic acid hydrogen ester is as follows: Example 8 Synthesis of DL-2-tert-butoxycarbonylamino-succinic acid 4-methyl ester To stirring DL-2-amino-succinic acid 4-methyl ester (dissolved in a solution of dioxane/H2O (2:1, 110 mL)) was added Na2CO3 (3.92 g, 0.037 mol). After CO2 release ceased, Na2CO3 (3.92 g, 0.037 mol) was added again, followed by Boc2O (8.87 g, 0.04 mol). The reaction mixture was stirred at 0 °C for 1 h (a white precipitate was formed within 30 min) and then continued to stir overnight at room temperature. After completion of the reaction, the solvent was removed under reduced pressure and the residue was washed with Et2O. The aqueous phase was acidified with saturated aqueous NaHCO3, then the pH was adjusted with NaHSO4 and extracted with Et2O. The organic phases were combined, dried with Na2SO4 and concentrated under reduced pressure to give 2-((tert-butoxycarbonyl)amino)-4-methoxy-4-oxobutanoic acid as a white solid (6.7 g, 74% yield).

References

[1] Patent: US2007/142415, 2007, A1. Location in patent: Page/Page column 18

2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid Suppliers

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856417-64-6, 2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acidRelated Search:

2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic acid

(S)-4-((2-((tert-Butoxycarbonyl))amino)ethyl)(2.4.6-trimethoxybenzyl)amino)-4-oxobutanoic acid

2-(tert-butoxycarbonylamino)-4-methoxy-4-oxobutanoic&nbsp

2-(tert-butoxycarbonyl)-4-Methoxy-4-oxobutanoic acid

BOC-DL-ASP(OME)

Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 4-methyl ester

Boc-DL-Asp(OMe)-OH

4-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-

4-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoic acid

Boc-DL-aspartate 4-methyl ester

856417-64-6