Benzoic acid, 2-broMo-4-fluoro-, ethyl ester
- Product Name
- Benzoic acid, 2-broMo-4-fluoro-, ethyl ester
- CAS No.
- 651341-68-3
- Chemical Name
- Benzoic acid, 2-broMo-4-fluoro-, ethyl ester
- Synonyms
- ethyl 2-bromo-4-fluorobenzoate;Benzoic acid, 2-broMo-4-fluoro-, ethyl ester
- CBNumber
- CB62500380
- Molecular Formula
- C9H8BrFO2
- Formula Weight
- 247.06
- MOL File
- 651341-68-3.mol
Benzoic acid, 2-broMo-4-fluoro-, ethyl ester Property
- Boiling point:
- 258.9±20.0 °C(Predicted)
- Density
- 1.504±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 099947
- Product name
- Ethyl 2-bromo-4-fluorobenzoate
- Packaging
- 250mg
- Price
- $62
- Updated
- 2021/12/16
- Product number
- 9506CZ
- Product name
- Ethyl2-bromo-4-fluorobenzoate
- Packaging
- 1g
- Price
- $68
- Updated
- 2021/12/16
- Product number
- PC300979
- Product name
- Ethyl2-bromo-4-fluorobenzoate
- Packaging
- 1g
- Price
- $73
- Updated
- 2021/12/16
- Product number
- PC300979
- Product name
- Ethyl2-bromo-4-fluorobenzoate
- Packaging
- 5g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- 2623-B-43
- Product name
- Ethyl 2-bromo-4-fluorobenzoate
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
Benzoic acid, 2-broMo-4-fluoro-, ethyl ester Chemical Properties,Usage,Production
Synthesis
64-17-5
1006-41-3
651341-68-3
2-Bromo-4-fluorobenzoic acid (2.37 g, 10.82 mmol) was dissolved in anhydrous ethanol (100 mL). Thionyl chloride (1.57 mL, 21.64 mmol) was slowly added under stirring, followed by heating the reaction mixture to reflux temperature and continuous stirring for 24 hours. Upon completion of the reaction, the reaction system was cooled to room temperature. Most of the solvent was removed by distillation under reduced pressure. The residue was washed with water and subsequently extracted with ethyl acetate (3 × 50 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Finally, the crude product was purified by silica gel column chromatography to afford ethyl 2-bromo-4-fluorobenzoate (2.29 g, 87% yield) as a colorless liquid.
References
[1] Patent: CN105555761, 2016, A. Location in patent: Paragraph 0358; 0359; 0360
Benzoic acid, 2-broMo-4-fluoro-, ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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