2-Amino-6-chloroimidazo[1,2-b]pyridazine
- Product Name
- 2-Amino-6-chloroimidazo[1,2-b]pyridazine
- CAS No.
- 887625-09-4
- Chemical Name
- 2-Amino-6-chloroimidazo[1,2-b]pyridazine
- Synonyms
- 6-Chloroimidazo[1,2-b]pyridazin-2-amine;6-Chloroimidazo[2,1-f]pyridazin-2-amine;2-Amino-6-chloroimidazo[1,2-b]pyridazine;Imidazo[1,2-b]pyridazin-2-amine, 6-chloro-;2-Amino-6-chloroimidazo[1,2-b]pyridazine ISO 9001：2015 REACH
- CBNumber
- CB62500759
- Molecular Formula
- C6H5ClN4
- Formula Weight
- 168.58
- MOL File
- 887625-09-4.mol
2-Amino-6-chloroimidazo[1,2-b]pyridazine Property
- Density
- 1.71
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 7.03±0.30(Predicted)
- Appearance
- Light yellow to green yellow Solid
- InChI
- InChI=1S/C6H5ClN4/c7-4-1-2-6-9-5(8)3-11(6)10-4/h1-3H,8H2
- InChIKey
- VEHNVCGISXDBIG-UHFFFAOYSA-N
- SMILES
- C12=NC(N)=CN1N=C(Cl)C=C2
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A595520
- Product name
- 2-Amino-6-chloroimidazo[1,2-b]pyridazine
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR951417
- Product name
- 2-Amino-6-chloroimidazo[1,2-b]pyridazine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- 3H30-5-44
- Product name
- 6-Chloroimidazo[1,2-b]pyridazin-2-amine
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- V8716
- Product name
- 2-Amino-6-chloroimidazo[1,2-b]pyridazine
- Packaging
- 1g
- Price
- $166
- Updated
- 2021/12/16
- Product number
- OR951417
- Product name
- 2-Amino-6-chloroimidazo[1,2-b]pyridazine
- Purity
- 95%
- Packaging
- 1g
- Price
- $250
- Updated
- 2021/12/16
2-Amino-6-chloroimidazo[1,2-b]pyridazine Chemical Properties,Usage,Production
Synthesis
947248-50-2
887625-09-4
Step E. N-(6-chloroimidazo[1,2-b]pyridazin-2-yl)-2,2,2-trifluoroacetamide (80 mg, 0.30 mmol) was dissolved in a mixed solvent of THF, methanol, and water (1 mL each), and anhydrous potassium carbonate (400 mg, 3 mmol) was added. The reaction mixture was heated to reflux for 8 hours. After completion of the reaction, it was cooled to room temperature and diluted with ethyl acetate and water. The organic and aqueous phases were separated, and the organic layer was washed with saturated saline (2 x 5 mL), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford 2-amino-6-chloroimidazo[1,2-b]pyridazine (45 mg, 90% yield). The product was characterized by 1H NMR (DMSO-d6, 300 MHz): δ 5.65 (s, 2H), 7.02 (d, 1H), 7.7 (d, 1H).
References
[1] Patent: US2009/163489, 2009, A1. Location in patent: Page/Page column 20
[2] Patent: WO2010/100144, 2010, A1. Location in patent: Page/Page column 163-164
2-Amino-6-chloroimidazo[1,2-b]pyridazine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-6-chloroimidazo[1,2-b]pyridazine manufacturers
- Product
- 2-Amino-6-chloroimidazo[1,2-b]pyridazine 887625-09-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-11-02